SCHEMBL4703362

SCHEMBL4703362

O=c1c2ccccc2c(=O)c2c1c1[nH]c3ccccc3c1c1c(=O)c3ccccc3c(=O)c21

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CHEK1 O14757 3/20 0.67
▸ NQO1 P15559 1/20 0.56
▸ PRKCA P17252 4/20 0.55
▸ CDK4 P11802 4/20 0.55
▸ CCND1 P24385 4/20 0.55
▸ MEN1 O00255 3/20 0.55
▸ KMT2A Q03164 3/20 0.55
▸ CDK5 Q00535 2/20 0.55
▸ CDK5R1 Q15078 2/20 0.55
▸ MAPT P10636 2/20 0.55
▸ PRKD3 O94806 2/20 0.55
▸ PRKCG P05129 2/20 0.55
▸ PRKCB P05771 2/20 0.55
▸ PRKACA P17612 2/20 0.55
▸ PRKACG P22612 2/20 0.55
▸ PRKACB P22694 2/20 0.55
▸ PRKCH P24723 2/20 0.55
▸ PRKCI P41743 2/20 0.55
▸ PRKCE Q02156 2/20 0.55
▸ PRKCQ Q04759 2/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13429474 0.90 CHEK1 (0.59) CHEK1NQO1PRKCACDK4CCND1
SCHEMBL21563828 0.85 KDM4E (0.67) CHEK1NQO1PRKCACDK4CCND1
SCHEMBL8667677 0.81 CDK2 (0.50) CHEK1NQO1CDK4CCND1MEN1
SCHEMBL2627635 0.81 CHEK1 (0.67) CHEK1PRKCACDK4CCND1MEN1
SCHEMBL4479809 0.81 CHEK1 (0.67) CHEK1PRKCACDK4CCND1MEN1
SCHEMBL29533066 0.80 CHEK1 (0.65) CHEK1PRKCACDK4CCND1MEN1
SCHEMBL30741432 0.80 CHEK1 (0.65) CHEK1PRKCACDK4CCND1MEN1
SCHEMBL12219428 0.80 CHEK1 (0.65) CHEK1PRKCACDK4CCND1MEN1
Bis-Imide A SCHEMBL31061368 0.80 CHEK1 (1.00) CHEK1PRKCACDK4CCND1MEN1
Bis-Imide A SCHEMBL5879127 0.80 CHEK1 (1.00) CHEK1PRKCACDK4CCND1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0562945-B1 Use of 5H-Dinaphto[2,3-a:2',3'-c]carbazole-6,11,12,17-tetrone in cosmetic, in particular in make-up composition OREAL (FR) 1996-02-07 — — EP claimed
EP-0562945-A1 Use of 5H-Dinaphto[2,3-a:2',3'-c]carbazole-6,11,12,17-tetrone in cosmetic, in particular in make-up composition L'OREAL (FR) 1993-09-29 — — EP claimed
EP-1158321-B1 Dichroic light polarizers with non-periodic arrangement of different polarizing elements NITTO DENKO CORP (JP) 2012-05-30 — — EP disclosed
EP-1158320-B1 Dichroic light polarizers NITTO DENKO CORP (JP) 2008-08-06 — — EP disclosed
EP-0792257-B1 MATERIAL FOR DICHROIC LIGHT POLARIZERS OPTIVA INC (US) 2003-04-09 — — EP disclosed
EP-1158321-A2 Dichroic light polarizers with non-periodic arrangement of different polarizing elements Optiva, Inc. (US) 2001-11-28 — — EP disclosed
EP-1158320-A2 Dichroic light polarizers Optiva, Inc. (US) 2001-11-28 — — EP disclosed
US-6049428-A COATING A SUBSTRATE WITH A SOLUTION OF AN ORGANIC DYE OCCURRING IN THE LYOTROPIC LIQUID-CRYSTAL STATE IN A SOLVENT WHILE SIMULTANEOUSLY ORIENTING THE DYE AND REMOVING THE SOLVENT OPTIVA, INC. (US) 2000-04-11 — — US disclosed
EP-0792257-A4 DICHROIC LIGHT POLARIZERS OPTIVA INC (US) 2000-01-19 — — EP disclosed
EP-0792257-A1 DICHROIC LIGHT POLARIZERS RUSSIAN TECHNOLOGY GROUP (US) 1997-09-03 — — EP disclosed
WO-1996016015-A1 DICHROIC LIGHT POLARIZERS RUSSIAN TECHNOLOGY GROUP (US) 1996-05-30 — — WO disclosed
EP-0562945-B1 Use of 5H-Dinaphto[2,3-a:2',3'-c]carbazole-6,11,12,17-tetrone in cosmetic, in particular in make-up composition OREAL (FR) 1996-02-07 — — EP disclosed
EP-0562945-B1 Use of 5H-Dinaphto[2,3-a:2',3'-c]carbazole-6,11,12,17-tetrone in cosmetic, in particular in make-up composition OREAL (FR) 1996-02-07 — — EP disclosed
EP-0562945-A1 Use of 5H-Dinaphto[2,3-a:2',3'-c]carbazole-6,11,12,17-tetrone in cosmetic, in particular in make-up composition L'OREAL (FR) 1993-09-29 — — EP disclosed
EP-0562945-A1 Use of 5H-Dinaphto[2,3-a:2',3'-c]carbazole-6,11,12,17-tetrone in cosmetic, in particular in make-up composition L'OREAL (FR) 1993-09-29 — — EP disclosed
EP-0562945-A1 Use of 5H-Dinaphto[2,3-a:2',3'-c]carbazole-6,11,12,17-tetrone in cosmetic, in particular in make-up composition L'OREAL (FR) 1993-09-29 — — EP disclosed
EP-0049873-B1 PROCESS FOR THE CARBAZOLATION OF ANTHRIMIDES CIBA-GEIGY AG (CH) 1985-01-16 — — EP disclosed
US-4349478-A Process for the carbazolation of anthrimides CIBA-GEIGY AG (CH) 1982-09-14 — — US disclosed
EP-0049873-A1 Process for the carbazolation of anthrimides CIBA-GEIGY AG (CH) 1982-04-21 — — EP disclosed
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