Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 5/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 4/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.40 |
| ▸ | PIK3CB | P42338 | 4/20 | 0.40 |
| ▸ | ATR | Q13535 | 11/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 2/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | BRAF | P15056 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL713914 | 0.91 | PIK3CG (0.41) | PIK3CGPIK3CDPIK3CAPIK3CBATR | |
| SCHEMBL470232 | 0.86 | PIK3CD (0.56) | PIK3CGPIK3CDPIK3CAPIK3CBATR | |
| SCHEMBL714352 | 0.84 | PIK3CG (0.58) | PIK3CGPIK3CDPIK3CAPIK3CBATR | |
| SCHEMBL715583 | 0.76 | PIK3CD (0.57) | PIK3CGPIK3CDPIK3CAPIK3CBATR | |
| SCHEMBL715596 | 0.76 | PIK3CD (0.56) | PIK3CGPIK3CDPIK3CAPIK3CBATR | |
| SCHEMBL713527 | 0.75 | PIK3CG (0.51) | PIK3CGPIK3CDPIK3CAPIK3CBTP53 | |
| SCHEMBL714369 | 0.74 | PIK3CG (0.46) | PIK3CGPIK3CDPIK3CAPIK3CBATR | |
| SCHEMBL19221910 | 0.74 | PIK3CD (0.72) | PIK3CGPIK3CDPIK3CAPIK3CBCNR2 | |
| SCHEMBL715410 | 0.74 | PIK3CG (0.69) | PIK3CGPIK3CDPIK3CAPIK3CB | |
| SCHEMBL715105 | 0.73 | PIK3CG (0.71) | PIK3CGPIK3CDPIK3CAPIK3CBATR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012032065-A1 | INDAZOLE DERIVATIVES FOR USE IN THE TREATMENT OF INFLUENZA VIRUS INFECTION | GLAXO GROUP LIMITED (GB) | 2012-03-15 | — | — | WO | disclosed |