Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB1 | P46663 | 18/20 | 0.78 |
| ▸ | F10 | P00742 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6045810 | 0.88 | BDKRB1 (1.00) | BDKRB1 | |
| SCHEMBL4703716 | 0.86 | BDKRB1 (0.78) | BDKRB1F10 | |
| SCHEMBL4702467 | 0.84 | BDKRB1 (0.65) | BDKRB1F10 | |
| SCHEMBL4702570 | 0.84 | BDKRB1 (0.65) | BDKRB1 | |
| SCHEMBL4706322 | 0.82 | BDKRB1 (0.69) | BDKRB1CHRM4 | |
| SCHEMBL6047131 | 0.81 | BDKRB1 (1.00) | BDKRB1CHRM4 | |
| SCHEMBL4705088 | 0.81 | BDKRB1 (0.78) | BDKRB1CHRM4 | |
| SCHEMBL4703544 | 0.81 | BDKRB1 (0.68) | BDKRB1 | |
| SCHEMBL4701038 | 0.79 | BDKRB1 (0.66) | BDKRB1CHRM4 | |
| SCHEMBL4702923 | 0.79 | BDKRB1 (0.68) | BDKRB1F10CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633348-B1 | 4- BROMO - 5 - (2- CHLORO - BENZOYLAMINO) - 1H - PYRAZOLE - 3 - CARBOXYLIC ACID AMIDE DERIVATIVES AND RELATED COMPOUNDS AS BRADYKININ B sb 1 /sb RECEPTOR ANTAGONISTS FOR THE TREATMENT OF INFLAMMATORY DISEASES | ELAN PHARM INC (US) | 2008-10-08 | — | — | EP | claimed |