Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 20/20 | 0.55 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.41 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5480192 | 1.00 | DPP4 (0.55) | DPP4DPP9DPP8 | |
| SCHEMBL645785 | 1.00 | DPP4 (0.55) | DPP4DPP9DPP8 | |
| SCHEMBL5480196 | 1.00 | DPP4 (0.55) | DPP4DPP9DPP8 | |
| SCHEMBL647855 | 0.85 | DPP4 (0.55) | DPP4DPP9 | |
| SCHEMBL4703069 | 0.84 | DPP4 (0.53) | DPP4DPP9 | |
| SCHEMBL4703067 | 0.84 | DPP4 (0.53) | DPP4DPP9 | |
| SCHEMBL647712 | 0.84 | DPP4 (0.53) | DPP4DPP9 | |
| SCHEMBL7046994 | 0.78 | DPP4 (0.54) | DPP4DPP9 | |
| SCHEMBL645715 | 0.77 | DPP4 (0.70) | DPP4DPP9DPP8 | |
| SCHEMBL649101 | 0.77 | DPP4 (0.56) | DPP4DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1560811-B9 | PHARMACEUTICAL COMPOSITIONS AS INHIBITORS OF DIPEPTIDYL PEPTIDASE-IV (DPP-IV) | ABBOTT LAB (US) | 2008-03-05 | — | — | EP | claimed |
| EP-1560811-B1 | PHARMACEUTICAL COMPOSITIONS AS INHIBITORS OF DIPEPTIDYL PEPTIDASE-IV (DPP-IV) | ABBOTT LAB (US) | 2007-08-01 | — | — | EP | claimed |
| EP-1560811-A2 | PHARMACEUTICAL COMPOSITIONS AS INHIBITORS OF DIPEPTIDYL PEPTIDASE-IV (DPP-IV) | Abbott Laboratories (US) | 2005-08-10 | — | — | EP | disclosed |
| WO-2004026822-A2 | PHARMACEUTICAL COMPOSITIONS AS INHIBITORS OF DIPEPTIDYL PEPTIDASE-IV (DPP-IV) | ABBOTT LABORATORIES (US) | 2004-04-01 | — | — | WO | disclosed |