Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP3 | P15309 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | TNF | P01375 | 1/20 | 0.35 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.35 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.35 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.35 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.35 |
| ▸ | WNT3A | P56704 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.34 |
| ▸ | SCD | O00767 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8548980 | 0.81 | ACP3 (0.38) | ACP3MEN1TNFCXCL8KMT2A | |
| SCHEMBL30903830 | 0.81 | ACP3 (0.50) | ACP3CNR2P2RX7OPRM1OPRD1 | |
| SCHEMBL9776265 | 0.81 | ACP3 (0.50) | ACP3CNR2P2RX7OPRM1OPRD1 | |
| SCHEMBL4708317 | 0.79 | HDAC4 (0.40) | KDM4E | |
| SCHEMBL4707217 | 0.76 | CYP2C19 (0.45) | KMT2AOPRM1OPRL1ALDH1A1KDM4E | |
| SCHEMBL4706914 | 0.76 | GAA (0.53) | L3MBTL1KDM4E | |
| SCHEMBL29369617 | 0.75 | EPHX2 (0.43) | MEN1TNFCXCL8KMT2APAX8 | |
| SCHEMBL162911 | 0.75 | EPHX2 (0.43) | MEN1TNFCXCL8KMT2APAX8 | |
| SCHEMBL4706109 | 0.75 | SMN1; SMN2 (0.47) | MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL4753826 | 0.75 | TRIM24 (0.36) | TRPM8ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1501809-B1 | TRIAZOLE DERIVATIVES AS TACHYKININ RECEPTOR ANTAGONISTS | LILLY CO ELI (US) | 2008-01-16 | — | — | EP | disclosed |