Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | KDM1A | O60341 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | DRD2 | P14416 | 3/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.40 |
| ▸ | RELA | Q04206 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 2/20 | 0.39 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CKS1B | P61024 | 1/20 | 0.35 |
| ▸ | SKP1 | P63208 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8635461 | 0.83 | EPHX2 (0.49) | EPHX2KDM1AMAOBDRD2ATM | |
| SCHEMBL14348198 | 0.83 | EPHX2 (0.49) | EPHX2KDM1AMAOBDRD2ATM | |
| SCHEMBL7328550 | 0.83 | EPHX2 (0.49) | EPHX2KDM1AMAOBDRD2ATM | |
| SCHEMBL8310630 | 0.83 | EPHX2 (0.49) | EPHX2KDM1AMAOBDRD2ATM | |
| SCHEMBL14016078 | 0.82 | EPHX2 (0.48) | EPHX2KDM1AMAOBDRD2ATM | |
| SCHEMBL4654164 | 0.82 | EPHX2 (0.48) | EPHX2KDM1AMAOBDRD2ATM | |
| SCHEMBL7423742 | 0.82 | EPHX2 (0.48) | EPHX2KDM1AMAOBDRD2ATM | |
| SCHEMBL4914877 | 0.81 | EPHX2 (0.47) | EPHX2KDM1AMAOBDRD2ATM | |
| SCHEMBL14015839 | 0.81 | EPHX2 (0.47) | EPHX2KDM1AMAOBDRD2ATM | |
| SCHEMBL5034414 | 0.81 | EPHX2 (0.47) | EPHX2KDM1AMAOBDRD2ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1658069-B1 | HETEROCYCLIC AMIDE DERIVATIVES WHICH POSSESS GLYCOGEN PHOSPHORYLASE INHIBITORY ACTIVITY | ASTRAZENECA AB (SE) | 2008-07-30 | — | — | EP | disclosed |