Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 20/20 | 0.79 |
| ▸ | AVPR1A | P37288 | 10/20 | 0.79 |
| ▸ | OXTR | P30559 | 2/20 | 0.79 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6627050 | 0.88 | AVPR2 (1.00) | AVPR2AVPR1AOXTR | |
| SCHEMBL6624436 | 0.86 | AVPR2 (0.76) | AVPR2AVPR1AOXTR | |
| SCHEMBL6624618 | 0.85 | AVPR2 (0.75) | AVPR2AVPR1AOXTR | |
| SCHEMBL4706073 | 0.84 | AVPR2 (0.77) | AVPR2AVPR1AOXTR | |
| SCHEMBL6624992 | 0.83 | AVPR2 (0.73) | AVPR2AVPR1AOXTR | |
| SCHEMBL6621758 | 0.83 | AVPR2 (0.77) | AVPR2AVPR1AOXTR | |
| SCHEMBL6622333 | 0.83 | AVPR2 (0.71) | AVPR2AVPR1AOXTR | |
| SCHEMBL6625293 | 0.82 | AVPR2 (0.76) | AVPR2AVPR1AOXTR | |
| SCHEMBL4707961 | 0.81 | AVPR2 (0.71) | AVPR2AVPR1AOXTR | |
| SCHEMBL6811363 | 0.80 | AVPR2 (0.67) | AVPR2AVPR1AOXTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1572694-B1 | PYRROLO[2,1-C][1,4] BENZODIAZEPINES AS VASOPRESSIN AGONISTS | WYETH CORP (US) | 2008-10-08 | — | — | EP | claimed |
| US-7138393-B2 | Biologically active vasopressin agonist metabolites | WYETH (US) | 2006-11-21 | — | — | US | claimed |
| EP-1572694-A1 | PYRROLO'2,1-C!'1,4! BENZODIAZEPINES AS VASOPRESSIN AGONISTS | Wyeth (US) | 2005-09-14 | — | — | EP | claimed |
| WO-2004060894-A1 | PYRROLO`2,1-C!`1,4! BENZODIAZEPINES AS VASOPRESSIN AGONISTS | WYETH (US) | 2004-07-22 | — | — | WO | claimed |
| US-20030134845-A1 | Biologically active vasopressin agonist metabolites | WYETH (US) | 2003-07-17 | — | — | US | claimed |
| EP-1572694-B1 | PYRROLO[2,1-C][1,4] BENZODIAZEPINES AS VASOPRESSIN AGONISTS | WYETH CORP (US) | 2008-10-08 | — | — | EP | disclosed |
| EP-1572694-B1 | PYRROLO[2,1-C][1,4] BENZODIAZEPINES AS VASOPRESSIN AGONISTS | WYETH CORP (US) | 2008-10-08 | — | — | EP | disclosed |
| US-7138393-B2 | Biologically active vasopressin agonist metabolites | WYETH (US) | 2006-11-21 | — | — | US | disclosed |
| WO-2004060894-A1 | PYRROLO`2,1-C!`1,4! BENZODIAZEPINES AS VASOPRESSIN AGONISTS | WYETH (US) | 2004-07-22 | — | — | WO | disclosed |
| US-20030134845-A1 | Biologically active vasopressin agonist metabolites | WYETH (US) | 2003-07-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030134845-A1 | Biologically active vasopressin agonist metabolites | AVPR2, AVPR1A, AVPR1B | AVPR2 1/4885AVPR1A 2/4885OXTR 28/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.