Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 5/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 4/20 | 0.39 |
| ▸ | PRKACA | P17612 | 4/20 | 0.39 |
| ▸ | CDK2 | P24941 | 4/20 | 0.39 |
| ▸ | GSK3B | P49841 | 4/20 | 0.39 |
| ▸ | PIM1 | P11309 | 3/20 | 0.39 |
| ▸ | HIPK2 | Q9H2X6 | 3/20 | 0.39 |
| ▸ | DAPK3 | O43293 | 3/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.39 |
| ▸ | PRKD3 | O94806 | 3/20 | 0.39 |
| ▸ | FLT3 | P36888 | 3/20 | 0.39 |
| ▸ | CLK2 | P49760 | 3/20 | 0.39 |
| ▸ | PRKX | P51817 | 3/20 | 0.39 |
| ▸ | JAK3 | P52333 | 3/20 | 0.39 |
| ▸ | CDK5 | Q00535 | 3/20 | 0.39 |
| ▸ | MAP4K2 | Q12851 | 3/20 | 0.39 |
| ▸ | CAMK2D | Q13557 | 3/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.39 |
| ▸ | PKN2 | Q16513 | 3/20 | 0.39 |
| ▸ | STK17A | Q9UEE5 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4707786 | 0.95 | AVPR1A (0.43) | CDC7MAP4K4PRKACACDK2GSK3B | |
| SCHEMBL4708709 | 0.89 | CDC7 (0.39) | CDC7MAP4K4PRKACACDK2GSK3B | |
| SCHEMBL4706112 | 0.86 | CDC7 (0.39) | CDC7MAP4K4PRKACACDK2GSK3B | |
| SCHEMBL4707548 | 0.84 | CDC7 (0.40) | CDC7MAP4K4PRKACACDK2GSK3B | |
| SCHEMBL4705191 | 0.82 | HTT (0.39) | CDC7MAP4K4PRKACACDK2GSK3B | |
| SCHEMBL4706990 | 0.81 | CDC7 (0.44) | CDC7MAP4K4PRKACACDK2GSK3B | |
| SCHEMBL4705520 | 0.81 | PTAFR (0.39) | CDC7MAP4K4PRKACACDK2GSK3B | |
| SCHEMBL4706961 | 0.80 | IDO1 (0.40) | CDC7MAP4K4PRKACACDK2GSK3B | |
| SCHEMBL4707828 | 0.80 | CDC7 (0.42) | CDC7MAP4K4PRKACACDK2GSK3B | |
| SCHEMBL4705551 | 0.80 | CDC7 (0.42) | CDC7MAP4K4PRKACACDK2GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1501809-B1 | TRIAZOLE DERIVATIVES AS TACHYKININ RECEPTOR ANTAGONISTS | LILLY CO ELI (US) | 2008-01-16 | — | — | EP | disclosed |