Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.48 |
| ▸ | DDO | Q99489 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | FLT3 | P36888 | 3/20 | 0.42 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.42 |
| ▸ | KIT | P10721 | 1/20 | 0.42 |
| ▸ | GABRP | O00591 | 1/20 | 0.41 |
| ▸ | GABRD | O14764 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | PDE5A | O76074 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18886845 | 0.87 | CA12 (0.45) | DAODDOKDM4EALDH1A1MAPT | |
| SCHEMBL4705953 | 0.87 | DAO (0.47) | DAODDOKDM4EALDH1A1MAPT | |
| SCHEMBL9263841 | 0.86 | DAO (0.46) | DAOKDM4EALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL18886870 | 0.86 | KDM4E (0.43) | KDM4EALDH1A1MAPTSMN1; SMN2HCRTR1 | |
| SCHEMBL3420884 | 0.83 | DAO (0.51) | DAODDOKDM4EALDH1A1MAPT | |
| SCHEMBL5260106 | 0.79 | KDM4E (0.48) | DAOKDM4EALDH1A1MAPTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL6984470 | 0.78 | KDM4E (0.47) | DAOKDM4EALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL701020 | 0.78 | KDM4E (0.57) | DAODDOKDM4EALDH1A1MAPT | |
| SCHEMBL4707549 | 0.77 | HCRTR1 (0.47) | KDM4EALDH1A1MAPTSMN1; SMN2HCRTR1 | |
| SCHEMBL9234415 | 0.75 | DAO (0.48) | DAOKDM4EALDH1A1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1625129-B1 | HETEROCYCLYL-SUBSTITUTED DIHYDROQUINAZOLINES AND USE THEREOF AS AN ANTIVIRAL AGENT | BAYER HEALTHCARE AG (DE) | 2008-03-05 | — | — | EP | disclosed |
| EP-1625129-A1 | HETEROCYCLYL-SUBSTITUTED DIHYDROQUINAZOLINES AND USE THEREOF AS AN ANTIVIRAL AGENT | Bayer HealthCare AG (DE) | 2006-02-15 | — | — | EP | disclosed |
| WO-2004099212-A1 | HETEROCYCLYL-SUBSTITUTED DIHYDROQUINAZOLINES AND USE THEREOF AS AN ANTIVIRAL AGENT | BAYER HEALTHCARE AG (DE) | 2004-11-18 | — | — | WO | disclosed |