SCHEMBL4708010

SCHEMBL4708010

CC(Br)Oc1c(Cl)cc(OCC=C(Cl)Cl)cc1Cl

nearest known ligand 0.38

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5239672 0.86 HTT (0.36) HTT
SCHEMBL4313190 0.83 HTT (0.35) HTT
Hydrochloric Acid SCHEMBL4472412 0.82 HTT (0.35) HTT
SCHEMBL8022495 0.81 HTT (0.36) HTT
SCHEMBL8407690 0.81 HTT (0.41) HTT
SCHEMBL7629872 0.81 HTT (0.35) HTT
SCHEMBL8025958 0.81 HTT (0.35) HTT
SCHEMBL7632232 0.81 HTT (0.35) HTT
SCHEMBL7635323 0.80 HTT (0.34) HTT
SCHEMBL13614127 0.80 HTT (0.42) HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1620401-A4 PHENYL SUBSTITUTED CYCLIC DERIVATIVES BAYER CROPSCIENCE AG (DE) 2008-08-13 EP disclosed
EP-1620401-A2 PHENYL SUBSTITUTED CYCLIC DERIVATIVES FMC CORPORATION (US) 2006-02-01 EP disclosed
WO-2004099145-A2 PHENYL SUBSTITUTED CYCLIC DERIVATIVES FMC CORPORATION (US) 2004-11-18 WO disclosed