Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4708589 | 0.95 | NR1H4 (0.56) | NR1H4KCNH2 | |
| SCHEMBL4522477 | 0.88 | NR1H4 (0.74) | NR1H4KCNH2 | |
| SCHEMBL1964410 | 0.84 | NR1H4 (0.80) | NR1H4KCNH2 | |
| SCHEMBL4526019 | 0.84 | NR1H4 (0.72) | NR1H4KCNH2 | |
| SCHEMBL4711292 | 0.82 | NR1H4 (0.50) | NR1H4 | |
| SCHEMBL1969196 | 0.82 | NR1H4 (0.79) | NR1H4KCNH2 | |
| SCHEMBL4522479 | 0.81 | NR1H4 (0.47) | NR1H4KCNH2 | |
| SCHEMBL4760883 | 0.80 | NR1H4 (0.80) | NR1H4KCNH2 | |
| SCHEMBL1968461 | 0.80 | NR1H4 (0.82) | NR1H4KCNH2 | |
| SCHEMBL1965284 | 0.80 | NR1H4 (0.82) | NR1H4KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1963331-A1 | AZEPINOINDOLE DERIVATIVES AS PHARMACEUTICAL AGENTS | Exelixis, Inc. (US) | 2008-09-03 | — | — | EP | claimed |
| WO-2007070796-A1 | AZEPINOINDOLE DERIVATIVES AS PHARMACEUTICAL AGENTS | EXELIXIS, INC. (US) | 2007-06-21 | — | — | WO | claimed |
| EP-1963331-A1 | AZEPINOINDOLE DERIVATIVES AS PHARMACEUTICAL AGENTS | Exelixis, Inc. (US) | 2008-09-03 | — | — | EP | disclosed |
| WO-2007070796-A1 | AZEPINOINDOLE DERIVATIVES AS PHARMACEUTICAL AGENTS | EXELIXIS, INC. (US) | 2007-06-21 | — | — | WO | disclosed |