Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 16/20 | 0.70 |
| ▸ | BCR | P11274 | 6/20 | 0.70 |
| ▸ | KDR | P35968 | 3/20 | 0.70 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.70 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.70 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.70 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.70 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.70 |
| ▸ | KIT | P10721 | 6/20 | 0.60 |
| ▸ | PDGFRA | P16234 | 6/20 | 0.60 |
| ▸ | PDGFRB | P09619 | 5/20 | 0.60 |
| ▸ | LYN | P07948 | 4/20 | 0.60 |
| ▸ | LCK | P06239 | 3/20 | 0.60 |
| ▸ | FLT3 | P36888 | 3/20 | 0.60 |
| ▸ | DDR2 | Q16832 | 3/20 | 0.60 |
| ▸ | LDLR | P01130 | 2/20 | 0.60 |
| ▸ | PCSK9 | Q8NBP7 | 2/20 | 0.60 |
| ▸ | EPHB6 | O15197 | 1/20 | 0.60 |
| ▸ | CA12 | O43570 | 1/20 | 0.60 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1005305 | 0.91 | ABL1 (0.72) | ABL1BCRKDRADORA3NR1I2 | |
| Hydrochloric Acid SCHEMBL4600295 | 0.91 | ABL1 (0.71) | ABL1BCRKDRADORA3NR1I2 | |
| Hydrochloric Acid SCHEMBL1754053 | 0.90 | ABL1 (0.70) | ABL1BCRKDRADORA3NR1I2 | |
| SCHEMBL3362592 | 0.88 | ABL1 (0.58) | ABL1BCRKDRADORA3NR1I2 | |
| SCHEMBL4713847 | 0.86 | ABL1 (0.56) | ABL1BCRKDRADORA3NR1I2 | |
| Radotinib SCHEMBL3359952 | 0.83 | ABL1 (1.00) | ABL1BCRKDRADORA3NR1I2 | |
| Radotinib SCHEMBL29381661 | 0.83 | ABL1 (1.00) | ABL1BCRKDRADORA3NR1I2 | |
| Radotinib SCHEMBL29366343 | 0.83 | ABL1 (1.00) | ABL1BCRKDRADORA3NR1I2 | |
| Radotinib SCHEMBL15285797 | 0.82 | ABL1 (0.99) | ABL1BCRKDRADORA3NR1I2 | |
| Radotinib SCHEMBL30002961 | 0.82 | ABL1 (0.99) | ABL1BCRKDRADORA3NR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1922309-A1 | N-PHENYL-2-PYRIMIDINE-AMINE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | Il Yang Pharm. Co. Ltd. (KR) | 2008-05-21 | — | — | EP | claimed |
| WO-2007018325-A1 | N-PHENYL-2-PYRIMIDINE-AMINE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | IL-YANG PHARM. CO., LTD. (KR) | 2007-02-15 | — | — | WO | claimed |
| EP-1922309-A1 | N-PHENYL-2-PYRIMIDINE-AMINE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | Il Yang Pharm. Co. Ltd. (KR) | 2008-05-21 | — | — | EP | disclosed |
| WO-2007018325-A1 | N-PHENYL-2-PYRIMIDINE-AMINE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | IL-YANG PHARM. CO., LTD. (KR) | 2007-02-15 | — | — | WO | disclosed |