⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methane SCHEMBL28020339 | 0.95 | — | — | |
| Formaldehyde SCHEMBL1044592 | 0.91 | — | — | |
| Methane SCHEMBL28020376 | 0.91 | — | — | |
| Alcohol SCHEMBL6801060 | 0.80 | — | — | |
| SCHEMBL14370574 | 0.67 | — | — | |
| Dimethylamine SCHEMBL7603588 | 0.63 | — | — | |
| SCHEMBL1665889 | 0.59 | — | — | |
| SCHEMBL29236157 | 0.59 | — | — | |
| SCHEMBL441023 | 0.59 | — | — | |
| SCHEMBL10788545 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 536 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122079957-A | N-nitroso-pseudoscouring (NAB) purity standard substance and preparation method and application thereof | — | 2026-05-26 | — | — | CN | claimed |
| CN-122084338-A | N-nitrosamine mixed solution standard substance and preparation method thereof | — | 2026-05-26 | — | — | CN | claimed |
| CN-122084341-A | 4- (Methylnitrosamine) -1- (3-pyridyl) -1-butanone (NNK) purity standard substance, preparation method and application thereof | — | 2026-05-26 | — | — | CN | claimed |
| US-12544025-B2 | Determining a biological tissue structural marker for diagnosis of a disease | Arion Diagnostics, Inc. (US) | 2026-02-10 | — | — | US | claimed |
| CN-119355177-B | Detection method and detection kit for multiple tobacco exposure markers in urine | 中国疾病预防控制中心环境与健康相关产品安全所 | 2025-04-08 | — | — | CN | claimed |
| CN-119715877-A | Method for detecting cigarette smoke exposure biomarker based on nanofiber solid phase extraction | 东南大学 | 2025-03-28 | — | — | CN | claimed |
| CN-114641574-B | Method for altering alkaloid content in plants | 英美烟草(投资)有限公司 | 2025-01-07 | — | — | CN | claimed |
| CN-115453013-B | Method for enriching and detecting 4-methylnitrosamine-1- (3-pyridyl) -1-butanone in tobacco | 云南中烟工业有限责任公司 | 2024-12-03 | — | — | CN | claimed |
| CN-114014778-B | Device and method for preparing diazomethane through continuous liquid separation and drying | 山东科加工业技术研究院有限公司 | 2024-10-29 | — | — | CN | claimed |
| CN-118460769-A | Co-dominant SSR marker closely linked with NNK release gene qNNK in tobacco mainstream smoke and application | 云南省烟草农业科学研究院 | 2024-08-09 | — | — | CN | claimed |
| US-20160090356-A1 | METHODS FOR PREPARING D-THREO-METHYLPHENIDATE USING DIAZOMETHANE, AND COMPOSITIONS THEREOF | AMPAC FINE CHEMICALS LLC | 2016-03-31 | — | — | US | claimed |
| US-9233924-B2 | Methods for preparing D-threo methylphenidate using diazomethane, and compositions thereof | AMPAC FINE CHEMICALS LLC (US) | 2016-01-12 | — | — | US | claimed |
| US-20150259289-A1 | METHODS FOR PREPARING D-THREO METHYLPHENIDATE USING DIAZOMETHANE, AND COMPOSITIONS THEREOF | AMPAC FINE CHEMICALS LLC (US) | 2015-09-17 | — | — | US | claimed |
| CN-1980885-A | Method for producing gaseous diazoalkanes | DYNAMIT NOBEL AG (DE) | 2007-06-13 | — | — | CN | claimed |
| EP-0916648-B1 | Continuous process for diazomethane | AEROJET FINE CHEMICALS LLC (US) | 2002-01-23 | — | — | EP | claimed |
| EP-0916649-B1 | Large scale batch process for diazomethane | AEROJET FINE CHEMICALS LLC (US) | 2002-01-23 | — | — | EP | claimed |
| EP-0916648-A1 | Continuous process for diazomethane | AEROJET-GENERAL CORPORATION (US) | 1999-05-19 | — | — | EP | claimed |
| EP-0916649-A1 | Large scale batch process for diazomethane | AEROJET-GENERAL CORPORATION (US) | 1999-05-19 | — | — | EP | claimed |
| US-5854405-A | Continuous process for diazomethane from an n-methyl-n-nitrosoamine and from methylurea through n-methyl-n-nitrosourea | AEROJET-GENERAL CORPORATION (US) | 1998-12-29 | — | — | US | claimed |
| US-5817778-A | FROM AN N-METHYL-N-NITROSOAMINE, PHASE TRANSFER CATALYST | AEROJET-GENERAL CORPORATION (US) | 1998-10-06 | — | — | US | claimed |