⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20769474 | 0.65 | — | — | |
| SCHEMBL2357920 | 0.65 | — | — | |
| SCHEMBL28246367 | 0.61 | — | — | |
| SCHEMBL28281416 | 0.60 | — | — | |
| SCHEMBL692809 | 0.60 | — | — | |
| SCHEMBL2016425 | 0.60 | — | — | |
| SCHEMBL1934967 | 0.59 | — | — | |
| SCHEMBL4462207 | 0.57 | — | — | |
| SCHEMBL4966817 | 0.57 | CA1 (0.30) | — | |
| SCHEMBL1404391 | 0.56 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 81 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103435505-A | Method for synthesizing -salmeterol | NANJING UNIVERSITY OF TECHNOLOGY | 2013-12-11 | — | — | CN | claimed |
| CN-101180298-A | Novel antibiotic derivatives | ACTELION PHARMACEUTICALS LTD (CH) | 2008-05-14 | — | — | CN | claimed |
| WO-2023125681-A1 | HETEROCYCLIC COMPOUNDS | BEIGENE, LTD. (KY) | 2023-07-06 | — | — | WO | disclosed |
| EP-4136084-A1 | BCL-2 INHIBITOR | BeiGene, Ltd. (KY) | 2023-02-22 | — | — | EP | disclosed |
| CN-111518166-B | Peptidomimetics compound or pharmaceutically acceptable salt thereof, and preparation method and application thereof | 中国药科大学 | 2023-01-31 | — | — | CN | disclosed |
| WO-2021208963-A1 | BCL-2 INHIBITOR | BEIGENE, LTD. (KY) | 2021-10-21 | — | — | WO | disclosed |
| CN-110403939-A | For treating the tricyclic nitrogenous compound of N. gonorrhoeae infections | GLAXOSMITHKLINE INTELECTUAL PROPERTY DEV LTD | 2019-11-05 | — | — | CN | disclosed |
| CN-106659717-B | Tricyclic nitrogen-containing compounds for the treatment of neisseria gonorrhoeae infections | 葛兰素史密斯克莱知识产权发展有限公司 | 2019-09-06 | — | — | CN | disclosed |
| CN-110177787-A | Integrin antagonists | 圣路易斯大学 | 2019-08-27 | — | — | CN | disclosed |
| CN-106659717-A | Tricyclic nitrogen-containing compounds for the treatment of neisseria gonorrhoeae infections | 葛兰素史密斯克莱知识产权发展有限公司 | 2017-05-10 | — | — | CN | disclosed |
| EP-3074377-A1 | SUBSTITUTED BENZAMIDES AND METHODS OF USE THEREOF | Genentech, Inc. (US) | 2016-10-05 | — | — | EP | disclosed |
| WO-2004035569-A2 | NOVEL COMPOUNDS WITH ANTIBACTERIAL ACTIVITY | Morphochem Aktiengesellschaft für kombinatorische Chemie (DE) | 2004-04-29 | — | — | WO | disclosed |
| CN-1139584-C | Heterocyclic compounds, method for preparing and medicine compositions containing same | ɪά��ʵ���� | 2004-02-25 | — | — | CN | disclosed |
| WO-2003106452-A2 | ANTAGONISTS OF MELANIN CONCENTRATING HORMONE RECEPTOR | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2003-12-24 | — | — | WO | disclosed |
| CN-1396920-A | 1, 3-disubstituted pyrrolidines as alpha-2-adrenoreceptor antagonists | NOVARTIS AG (CH) | 2003-02-12 | — | — | CN | disclosed |
| CN-1373745-A | 3-amino-2-benzyl-1-phenyl-propane derivs. | GREULENTHAL GMBH (DE) | 2002-10-09 | — | — | CN | disclosed |
| CN-1332711-A | Vitamin D analogues | GALDERMA RES & DEV (FR) | 2002-01-23 | — | — | CN | disclosed |
| CN-1067071-C | Carboline derivatives | ICOS CORP (US) | 2001-06-13 | — | — | CN | disclosed |
| CN-1260789-A | Heterocyclic compounds, method for preparing and medicine compositions containing same | ADIR CO (FR) | 2000-07-19 | — | — | CN | disclosed |
| CN-1218471-A | Carboline derivatives | ICOS CORP (US) | 1999-06-02 | — | — | CN | disclosed |