⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16922198 | 1.00 | — | — | |
| SCHEMBL13741361 | 0.72 | — | — | |
| SCHEMBL2632640 | 0.72 | — | — | |
| SCHEMBL2632684 | 0.72 | — | — | |
| SCHEMBL17922042 | 0.72 | — | — | |
| SCHEMBL24739021 | 0.72 | — | — | |
| SCHEMBL13092868 | 0.72 | — | — | |
| SCHEMBL9965110 | 0.72 | — | — | |
| SCHEMBL10029408 | 0.72 | — | — | |
| SCHEMBL10084333 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1686113-B1 | Inhibitors of aspartyl protease | VERTEX PHARMA (US) | 2011-11-23 | — | — | EP | disclosed |
| EP-1984331-B1 | PYRROLIDINE DERIVATIVES AS ERK INHIBITORS | SCHERING CORP (US) | 2010-10-20 | — | — | EP | disclosed |
| US-7754431-B2 | selecting a taxane or taxane derivative for chemotherapy of the cancer patient when the TLE3 (transducin-like enhancer of split 3) expression is present; paclitaxel; docetaxel | APPLIED GENOMICS, INC. (US) | 2010-07-13 | — | — | US | disclosed |
| US-20100062444-A1 | selecting a taxane or taxane derivative for chemotherapy of the cancer patient when the TLE3 (transducin-like enhancer of split 3) expression is present; paclitaxel; docetaxel | APPLIED GENOMICS, INC. (US) | 2010-03-11 | — | — | US | disclosed |
| US-20100029756-A1 | NOVEL COMPOSITIONS CONTAINING ISOLATED TETRAMERIC TYPE A PROANTHOCYANADIN AND METHODS OF USE AND MANUFACTURE | PHENOLICS, LLC | 2010-02-04 | — | — | US | disclosed |
| WO-2009073534-A2 | BICYCLIC PPAT INHIBITORS AS ANTIBACTERIAL AGENTS | MAXTHERA INC. (US) | 2009-06-11 | — | — | WO | disclosed |
| EP-1628977-B1 | ANTIBIOTIC TETRAHYDRO-b-CARBOLINE DERIVATIVES | OSCIENT PHARMACEUTICALS (US) | 2008-11-12 | — | — | EP | disclosed |
| EP-1379249-A4 | FUSED CYCLIC SUCCINIMIDE COMPOUNDS AND ANALOGS THEREOF, MODULATORS OF NUCLEAR HORMONE RECEPTOR FUNCTION | BRISTOL MYERS SQUIBB CO (US) | 2008-01-09 | — | — | EP | disclosed |
| EP-1379249-A1 | FUSED CYCLIC SUCCINIMIDE COMPOUNDS AND ANALOGS THEREOF, MODULATORS OF NUCLEAR HORMONE RECEPTOR FUNCTION | Bristol-Myers Squibb Company (US) | 2004-01-14 | — | — | EP | disclosed |
| WO-2002067939-A1 | FUSED CYCLIC SUCCINIMIDE COMPOUNDS AND ANALOGS THEREOF, MODULATORS OF NUCLEAR HORMONE RECEPTOR FUNCTION | BRISTOL-MYERS SQUIBB COMPANY (US) | 2002-09-06 | — | — | WO | disclosed |