⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7164477 | 0.77 | — | — | |
| SCHEMBL27644928 | 0.76 | TYR (0.41) | — | |
| SCHEMBL11121532 | 0.75 | — | — | |
| SCHEMBL11081057 | 0.75 | — | — | |
| SCHEMBL2981174 | 0.75 | — | — | |
| SCHEMBL21962268 | 0.75 | — | — | |
| SCHEMBL22521369 | 0.75 | SLC6A2 (0.33) | — | |
| SCHEMBL20733705 | 0.75 | — | — | |
| SCHEMBL2990023 | 0.75 | SLC6A4 (0.38) | — | |
| SCHEMBL9631536 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119431323-A | Heterobicyclic amides as CD38 inhibitors | 贝林格尔·英格海姆国际有限公司 | 2025-02-14 | — | — | CN | disclosed |
| CN-114423753-B | Heterobicyclic amides as CD38 inhibitors | 里邦医疗公司 | 2024-09-17 | — | — | CN | disclosed |
| CN-102365277-B | JUN N-terminal kinase inhibitors | ELAN PHARMACEUTICALS, INC. (US) | 2015-11-25 | — | — | CN | disclosed |
| US-8119645-B2 | Fungicide hydroximoyl-tetrazole derivatives | BAYER CROPSCIENCE AG (DE) | 2012-02-21 | — | — | US | disclosed |
| EP-2019825-B9 | INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION | BOEHRINGER INGELHEIM INT (DE) | 2011-01-26 | — | — | EP | disclosed |
| EP-2019825-B1 | INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION | BOEHRINGER INGELHEIM INT (DE) | 2010-09-01 | — | — | EP | disclosed |
| US-20100197657-A1 | 2-ARYL OR HETEROARYL INDOLE DERIVATIVES | CHANG RONALD K | 2010-08-05 | — | — | US | disclosed |
| US-20090291969-A1 | Fungicide hydroximoyl-tetrazole derivatives | BAYER CROPSCIENCE AG (DE) | 2009-11-26 | — | — | US | disclosed |
| EP-2007772-A1 | THIAZOLYL-DIHYDROQUINAZOLINES | Boehringer Ingelheim International GmbH (DE) | 2008-12-31 | — | — | EP | disclosed |
| WO-2007131350-A1 | INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-11-22 | — | — | WO | disclosed |
| EP-0142027-A1 | 5-Substituted-delta-2-imidazolinyl-thio ethers, and process for their production | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-05-22 | — | — | EP | disclosed |
| EP-0008077-B1 | PROSTAGLANDIN DERIVATIVES WITH A DELTA-2-PGF2 STRUCTURE OR A DELTA-2-PGE2 STRUCTURE, PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICAMENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1983-11-16 | — | — | EP | disclosed |
| EP-0065200-A2 | Thiolactime ethers of delta-1-pyrrolidine, and their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-11-24 | — | — | EP | disclosed |
| EP-0055851-A1 | 11-Deoxy-hetero-imino-prostacyclins, processes for their preparation and their use as medicaments | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-07-14 | — | — | EP | disclosed |
| US-4312882-A | ANTICOAGULANTS, HYPOTENSIVE AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-01-26 | — | — | US | disclosed |
| US-4304783-A | ANTITHROMBOTIC, ANTIINFARCT, HYPOTENSIVE AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-12-08 | — | — | US | disclosed |
| US-4296121-A | HYPOTENSIVE AGENTS, ANTICOAGULANTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-10-20 | — | — | US | disclosed |
| EP-0029527-A2 | Prostaglandin derivatives of the 6-keto-PGA1 series, process for their production as well as their use in medicaments and their intermediate products | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-06-03 | — | — | EP | disclosed |
| EP-0013955-A1 | Analogues of prostacyclin, their intermediates, a process for their preparation and medicaments containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1980-08-06 | — | — | EP | disclosed |
| EP-0008077-A2 | Prostaglandin derivatives with a delta-2-PGF2 structure or a delta-2-PGE2 structure, process for their preparation and their use as medicaments | HOECHST AKTIENGESELLSCHAFT (DE) | 1980-02-20 | — | — | EP | disclosed |