SCHEMBL4711792

SCHEMBL4711792

O=C(O)c1nn(-c2ccc(F)cc2F)c2c1CS(=O)(=O)CC2Cc1cccc(F)c1

nearest known ligand 0.42

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 20/20 0.42
CNR1 P21554 8/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3076479 0.87 CNR2 (0.45) CNR2CNR1
SCHEMBL176466 0.84 CNR2 (0.43) CNR2CNR1
SCHEMBL4711951 0.82 CNR2 (0.33) CNR2CNR1
SCHEMBL13867028 0.81 CNR2 (0.56) CNR2CNR1
SCHEMBL13867202 0.79 CNR2 (0.35) CNR2CNR1
SCHEMBL4708927 0.78 CNR2 (0.40) CNR2CNR1
SCHEMBL3893139 0.78 CNR2 (0.40) CNR2CNR1
SCHEMBL646267 0.77 CNR2 (0.44) CNR2CNR1
SCHEMBL4712180 0.77 CNR2 (0.39) CNR2CNR1
SCHEMBL3469566 0.76 CNR2 (0.43) CNR2CNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1863479-B1 TETRAHYDROTHIOPYRANO PYRAZOLE CANNABINOID MODULATORS CROSS REFERENCE TO RELATED APPLICATIONS JANSSEN PHARMACEUTICA NV (BE) 2008-12-10 EP disclosed