Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 20/20 | 0.51 |
| ▸ | MC5R | P33032 | 2/20 | 0.51 |
| ▸ | MC3R | P41968 | 2/20 | 0.51 |
| ▸ | MC1R | Q01726 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL47133 | 0.91 | MC4R (0.60) | MC4RMC5RMC3RMC1R | |
| SCHEMBL47098 | 0.91 | MC4R (0.52) | MC4RMC5RMC3RMC1R | |
| SCHEMBL10069669 | 0.91 | MC4R (0.58) | MC4RMC5RMC3RMC1R | |
| SCHEMBL47194 | 0.90 | MC4R (0.51) | MC4RMC5RMC3RMC1R | |
| SCHEMBL47122 | 0.90 | MC4R (0.59) | MC4RMC5RMC3RMC1R | |
| SCHEMBL47257 | 0.89 | MC4R (0.54) | MC4RMC5RMC3RMC1R | |
| SCHEMBL46877 | 0.89 | MC4R (0.62) | MC4RMC5RMC3RMC1R | |
| SCHEMBL47169 | 0.89 | MC4R (0.54) | MC4RMC5RMC3RMC1R | |
| SCHEMBL46842 | 0.89 | MC4R (0.61) | MC4RMC5RMC3RMC1R | |
| SCHEMBL47165 | 0.88 | MC4R (0.53) | MC4RMC5RMC3RMC1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012003576-A1 | IMIDAZOPYRIDINE, IMIDAZOPYRIMIDINE AND IMIDAZOPYRAZINE DERIVATIVES AS MELANOCORTIN-4 RECEPTOR MODULATORS | Université de Montréal (CA) | 2012-01-12 | — | — | WO | disclosed |