Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 10/20 | 0.57 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4713004 | 0.84 | GRM5 (0.50) | GRM5SLC6A2 | |
| SCHEMBL4713235 | 0.82 | GRM5 (0.68) | GRM5SLC6A2 | |
| SCHEMBL4710329 | 0.74 | CYP1A2 (0.46) | GRM5ABL1 | |
| SCHEMBL4713011 | 0.74 | GRM5 (0.49) | GRM5ABL1 | |
| SCHEMBL3877004 | 0.73 | GRM5 (1.00) | GRM5SLC6A2ABL1 | |
| SCHEMBL4710981 | 0.73 | GRM5 (0.47) | GRM5ABL1 | |
| SCHEMBL4712681 | 0.73 | GRM5 (0.42) | GRM5 | |
| SCHEMBL4712038 | 0.73 | GRM5 (0.49) | GRM5 | |
| Hydrochloric Acid SCHEMBL4654166 | 0.72 | GRM5 (0.97) | GRM5SLC6A2ABL1 | |
| SCHEMBL4712557 | 0.72 | GRM5 (0.57) | GRM5SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0998459-B1 | PYRIDINE DERIVATIVES | NOVARTIS AG (CH) | 2008-04-23 | — | — | EP | claimed |
| EP-0998459-B1 | PYRIDINE DERIVATIVES | NOVARTIS AG (CH) | 2008-04-23 | — | — | EP | disclosed |