Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | RYR2 | Q92736 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4714738 | 0.78 | MEN1 (0.39) | MEN1ALDH1A1GAAKMT2ARYR2 | |
| SCHEMBL2800209 | 0.74 | CCR1 (0.37) | MEN1ALDH1A1GAAKMT2ARYR2 | |
| SCHEMBL12692898 | 0.74 | MEN1 (0.36) | MEN1ALDH1A1GAAKMT2ARYR2 | |
| SCHEMBL14610993 | 0.73 | KDM4E (0.37) | MEN1ALDH1A1GAAKMT2ARYR2 | |
| SCHEMBL2051657 | 0.69 | GAA (0.50) | MEN1ALDH1A1GAAKMT2ARYR2 | |
| SCHEMBL5760469 | 0.69 | MEN1 (0.41) | MEN1ALDH1A1GAAKMT2ARYR2 | |
| SCHEMBL5298418 | 0.68 | RYR2 (0.39) | MEN1ALDH1A1GAAKMT2ARYR2 | |
| SCHEMBL910393 | 0.67 | MEN1 (0.39) | MEN1ALDH1A1GAAKMT2ARYR2 | |
| SCHEMBL15691803 | 0.66 | UHRF1 (0.35) | MEN1ALDH1A1GAAKMT2ARYR2 | |
| SCHEMBL8168165 | 0.64 | ITGAV (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1216230-B1 | FUSED CYCLOHEPTANE AND FUSED AZACYCLOHEPTANE COMPOUNDS AND THEIR USE AS INTEGRIN RECEPTOR ANTAGONISTS | AMGEN INC (US) | 2008-04-23 | — | — | EP | disclosed |