Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 20/20 | 0.83 |
| ▸ | MAPK3 | P27361 | 3/20 | 0.78 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.78 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.78 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.78 |
| ▸ | GP6 | Q9HCN6 | 1/20 | 0.75 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4715156 | 1.00 | SYK (0.83) | SYKMAPK3MAPK1KCNH2AURKB | |
| SCHEMBL1353793 | 0.91 | SYK (1.00) | SYKMAPK3MAPK1KCNH2AURKB | |
| SCHEMBL1353792 | 0.91 | SYK (1.00) | SYKMAPK3MAPK1KCNH2AURKB | |
| SCHEMBL16195116 | 0.88 | SYK (1.00) | SYKMAPK3MAPK1KCNH2AURKB | |
| SCHEMBL4710859 | 0.88 | SYK (0.76) | SYKMAPK3MAPK1KCNH2AURKB | |
| SCHEMBL4710858 | 0.88 | SYK (0.76) | SYKMAPK3MAPK1KCNH2AURKB | |
| SCHEMBL16194748 | 0.87 | SYK (0.81) | SYKMAPK3MAPK1KCNH2AURKB | |
| SCHEMBL2627287 | 0.87 | SYK (1.00) | SYKMAPK3MAPK1KCNH2AURKB | |
| SCHEMBL1355005 | 0.87 | SYK (1.00) | SYKMAPK3MAPK1KCNH2AURKB | |
| SCHEMBL2386521 | 0.86 | SYK (1.00) | SYKMAPK3MAPK1KCNH2AURKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1054004-B1 | NOVEL PYRIMIDINE-5-CARBOXAMIDE DERIVATIVES | ASTELLAS PHARMA INC (JP) | 2008-07-16 | — | — | EP | claimed |