Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | GRM5 | P41594 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | THPO | P40225 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4715212 | 1.00 | KMT2A (0.51) | KMT2AALDH1A1MEN1SMN1; SMN2NPC1 | |
| SCHEMBL4715215 | 1.00 | KMT2A (0.51) | KMT2AALDH1A1MEN1SMN1; SMN2NPC1 | |
| SCHEMBL4710057 | 0.88 | KMT2A (0.54) | KMT2AALDH1A1MEN1SMN1; SMN2NPC1 | |
| SCHEMBL4710056 | 0.88 | KMT2A (0.54) | KMT2AALDH1A1MEN1SMN1; SMN2NPC1 | |
| SCHEMBL4710865 | 0.86 | MEN1 (0.50) | KMT2AALDH1A1MEN1SMN1; SMN2NPC1 | |
| SCHEMBL4710866 | 0.86 | MEN1 (0.50) | KMT2AALDH1A1MEN1SMN1; SMN2NPC1 | |
| SCHEMBL4713809 | 0.85 | KDM4E (0.55) | KMT2AALDH1A1MEN1SMN1; SMN2NPC1 | |
| SCHEMBL4713812 | 0.85 | KDM4E (0.55) | KMT2AALDH1A1MEN1SMN1; SMN2NPC1 | |
| SCHEMBL27513842 | 0.84 | GRM5 (0.49) | KMT2AALDH1A1SMN1; SMN2NPC1GRM5 | |
| Cyclohexane SCHEMBL4714543 | 0.83 | MEN1 (0.56) | KMT2AALDH1A1MEN1SMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0998459-B1 | PYRIDINE DERIVATIVES | NOVARTIS AG (CH) | 2008-04-23 | — | — | EP | claimed |
| EP-0998459-B1 | PYRIDINE DERIVATIVES | NOVARTIS AG (CH) | 2008-04-23 | — | — | EP | disclosed |