Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.45 |
| ▸ | MRGPRX4 | Q96LA9 | 6/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 6/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | RXRB | P28702 | 1/20 | 0.38 |
| ▸ | RXRG | P48443 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12275459 | 0.82 | FFAR4 (0.48) | FFAR4MRGPRX4MCHR1MEN1KMT2A | |
| SCHEMBL3133338 | 0.81 | FFAR4 (0.42) | FFAR4MRGPRX4MCHR1MEN1KMT2A | |
| SCHEMBL3142184 | 0.80 | MAPT (0.44) | FFAR4MEN1KMT2AMAPTTDP1 | |
| SCHEMBL4715362 | 0.79 | FFAR4 (0.44) | FFAR4MRGPRX4MCHR1PTPN1MAPT | |
| SCHEMBL3135075 | 0.76 | FFAR4 (0.44) | FFAR4MRGPRX4MCHR1MEN1KMT2A | |
| SCHEMBL8913036 | 0.75 | MEN1 (0.51) | MEN1KMT2AMAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL8913307 | 0.74 | HCRTR2 (0.43) | KMT2AMAPTTDP1SMN1; SMN2L3MBTL1 | |
| SCHEMBL8915218 | 0.74 | FFAR4 (0.46) | FFAR4MRGPRX4MCHR1L3MBTL1 | |
| SCHEMBL12275460 | 0.71 | FFAR4 (0.47) | FFAR4MRGPRX4MCHR1RXRARXRB | |
| SCHEMBL3133342 | 0.70 | FFAR4 (0.41) | FFAR4MRGPRX4MCHR1RXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1957073-A2 | MEDICINAL DRUG | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2008-08-20 | — | — | EP | disclosed |
| WO-2007066784-A2 | DIARYLETHER DERIVATIVES AS ANTITUMOR AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2007-06-14 | — | — | WO | disclosed |
| EP-1773797-A2 | AROMATIC COMPOUNDS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2007-04-18 | — | — | EP | disclosed |
| WO-2006014012-A2 | AROMATIC COMPOUNDS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-02-09 | — | — | WO | disclosed |