Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 5/20 | 0.59 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.59 |
| ▸ | GPR17 | Q13304 | 7/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29009735 | 0.88 | FFAR4 (0.47) | FFAR1FFAR4GPR17NPSR1CNR1 | |
| SCHEMBL30428306 | 0.86 | F13A1 (0.48) | FFAR1FFAR4GPR17NPSR1 | |
| SCHEMBL28321275 | 0.85 | FFAR1 (0.46) | FFAR1FFAR4GPR17CNR1 | |
| SCHEMBL14793754 | 0.85 | FFAR1 (0.57) | FFAR1FFAR4GPR17NPSR1KEAP1 | |
| SCHEMBL29009903 | 0.84 | F13A1 (0.52) | FFAR1FFAR4GPR17 | |
| SCHEMBL31641818 | 0.83 | TAAR1 (0.43) | FFAR1FFAR4GPR17CNR1CES2 | |
| SCHEMBL4714251 | 0.81 | CNR1 (0.43) | FFAR1FFAR4GPR17CNR1CES2 | |
| SCHEMBL18606621 | 0.79 | GPR17 (0.59) | FFAR1FFAR4GPR17NPSR1KEAP1 | |
| SCHEMBL13064939 | 0.79 | TAAR1 (0.59) | FFAR1FFAR4GPR17TAAR1 | |
| SCHEMBL4714927 | 0.78 | FFAR1 (0.59) | FFAR1FFAR4GPR17KEAP1CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1337517-B1 | PYRIMIDINONE DERIVATIVES AND THEIR USE IN THE TREATMENT OF ATHEROSCLEROSIS | SMITHKLINE BEECHAM PLC (GB) | 2008-11-26 | — | — | EP | disclosed |