Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 4/20 | 0.49 |
| ▸ | TTR | P02766 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4258728 | 1.00 | SCD (0.49) | SCDTTRCYP3A4CYP2D6 | |
| SCHEMBL31162729 | 0.95 | SCD (0.54) | SCDCYP3A4CYP2D6 | |
| SCHEMBL4258594 | 0.85 | SCD (0.55) | SCDTTRCYP3A4CYP2D6 | |
| SCHEMBL4253957 | 0.84 | SCD (0.59) | SCDCYP3A4CYP2D6 | |
| SCHEMBL31162681 | 0.84 | SCD (0.59) | SCDCYP3A4CYP2D6 | |
| SCHEMBL4163345 | 0.82 | TTR (0.50) | SCDTTR | |
| SCHEMBL4255167 | 0.82 | SCD (0.56) | SCDTTRCYP3A4CYP2D6 | |
| SCHEMBL31162613 | 0.82 | — | — | |
| SCHEMBL4252696 | 0.81 | SCD (0.57) | SCDCYP3A4CYP2D6 | |
| SCHEMBL4154385 | 0.80 | SCD (0.39) | SCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1910352-A1 | HETEROAROMATIC COMPOUNDS AS INHIBITORS OF STEAROYL-COENZYME A DELTA-9 DESATURASE | Merck Frosst Canada Ltd. (CA) | 2008-04-16 | — | — | EP | disclosed |
| WO-2007009236-A1 | HETEROAROMATIC COMPOUNDS AS INHIBITORS OF STEAROYL-COENZYME A DELTA-9 DESATURASE | MERCK FROSST CANADA LTD. (CA) | 2007-01-25 | — | — | WO | disclosed |