Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR8 | P51685 | 2/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 16/20 | 0.40 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.37 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3922435 | 0.92 | CCR8 (0.43) | CCR8KCNH2 | |
| Hydrochloric Acid SCHEMBL3922431 | 0.92 | CCR8 (0.43) | CCR8KCNH2 | |
| SCHEMBL4718242 | 0.90 | CCR8 (0.47) | CCR8KCNH2KCNQ1CACNA1C | |
| SCHEMBL3925037 | 0.86 | CCR8 (0.52) | CCR8KCNH2KCNQ1CACNA1C | |
| SCHEMBL3925031 | 0.86 | CCR8 (0.52) | CCR8KCNH2KCNQ1CACNA1C | |
| Hydrochloric Acid SCHEMBL4716962 | 0.85 | CCR8 (0.52) | CCR8KCNH2KCNQ1CACNA1C | |
| Hydrochloric Acid SCHEMBL4716967 | 0.85 | CCR8 (0.52) | CCR8KCNH2KCNQ1CACNA1C | |
| SCHEMBL3919654 | 0.85 | CCR8 (0.67) | CCR8KCNH2KCNQ1CACNA1C | |
| SCHEMBL3919647 | 0.85 | CCR8 (0.67) | CCR8KCNH2KCNQ1CACNA1C | |
| Hydrochloric Acid SCHEMBL3923830 | 0.84 | CCR8 (0.66) | CCR8KCNH2KCNQ1CACNA1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1567520-B1 | QUINOLINES AND NITROGENATED DERIVATIVES THEREOF AND THEIR USE AS ANTIBACTERIAL AGENTS | GLAXO GROUP LTD (GB) | 2008-10-15 | — | — | EP | claimed |