Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 20/20 | 0.68 |
| ▸ | HSP90AB1 | P08238 | 19/20 | 0.68 |
| ▸ | TRAP1 | Q12931 | 7/20 | 0.50 |
| ▸ | HSP90B1 | P14625 | 6/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5145327 | 0.90 | HSP90AA1 (0.74) | HSP90AA1HSP90AB1TRAP1HSP90B1 | |
| SCHEMBL4709172 | 0.90 | HSP90AA1 (0.74) | HSP90AA1HSP90AB1TRAP1HSP90B1 | |
| SCHEMBL5145464 | 0.90 | HSP90AA1 (0.69) | HSP90AA1HSP90AB1TRAP1HSP90B1 | |
| SCHEMBL5145460 | 0.90 | HSP90AA1 (0.69) | HSP90AA1HSP90AB1TRAP1HSP90B1 | |
| SCHEMBL4707244 | 0.88 | HSP90AA1 (0.68) | HSP90AA1HSP90AB1TRAP1HSP90B1 | |
| SCHEMBL4707363 | 0.87 | HSP90AB1 (0.69) | HSP90AA1HSP90AB1TRAP1HSP90B1 | |
| SCHEMBL4707473 | 0.86 | HSP90AA1 (0.65) | HSP90AA1HSP90AB1TRAP1HSP90B1 | |
| SCHEMBL4706795 | 0.84 | HSP90AB1 (0.71) | HSP90AA1HSP90AB1TRAP1HSP90B1 | |
| SCHEMBL5148096 | 0.82 | HSP90AA1 (0.65) | HSP90AA1HSP90AB1TRAP1HSP90B1 | |
| SCHEMBL5148097 | 0.82 | HSP90AA1 (0.65) | HSP90AA1HSP90AB1TRAP1HSP90B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1991525-A1 | CYCLOHEXYLAMINO, BENZENE, PYRIDINE, AND PYRIDAZINE DERIVATIVES | Serenex, Inc. (US) | 2008-11-19 | — | — | EP | claimed |
| WO-2007101156-A1 | CYCLOHEXYLAMINO, BENZENE, PYRIDINE, AND PYRIDAZINE DERIVATIVES | SERENEX, INC. (US) | 2007-09-07 | — | — | WO | claimed |