Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.60 |
| ▸ | EGFR | P00533 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24691227 | 1.00 | TDP1 (0.60) | TDP1EGFRLMNATSHRALDH1A1 | |
| SCHEMBL24691964 | 1.00 | TDP1 (0.60) | TDP1EGFRLMNATSHRALDH1A1 | |
| SCHEMBL3221436 | 0.91 | TSHR (0.56) | TDP1EGFRLMNATSHRALDH1A1 | |
| SCHEMBL113328 | 0.88 | TDP1 (0.67) | TDP1LMNATSHRALDH1A1L3MBTL1 | |
| SCHEMBL17978239 | 0.88 | TDP1 (0.67) | TDP1LMNATSHRALDH1A1L3MBTL1 | |
| SCHEMBL29449291 | 0.88 | TDP1 (0.67) | TDP1LMNATSHRALDH1A1L3MBTL1 | |
| SCHEMBL63546 | 0.86 | TDP1 (0.69) | TDP1LMNATSHRALDH1A1L3MBTL1 | |
| SCHEMBL4922318 | 0.86 | TDP1 (0.69) | TDP1LMNATSHRALDH1A1L3MBTL1 | |
| SCHEMBL597679 | 0.86 | TDP1 (0.69) | TDP1LMNATSHRALDH1A1L3MBTL1 | |
| SCHEMBL32671557 | 0.86 | TDP1 (0.69) | TDP1LMNATSHRALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101404985-A | Autoimmune conditions and NADPH oxidase defects | BIOVITRUM AB PUBL (SE) | 2009-04-08 | — | — | CN | disclosed |
| EP-2004159-A1 | AUTOIMMUNE CONDITIONS AND NADPH OXIDASE DEFECTS | Biovitrum AB (publ) (SE) | 2008-12-24 | — | — | EP | disclosed |
| US-20080051451-A1 | Autoimmune conditions and NADPH oxidase defects | BIOVITRUM AB (SE) | 2008-02-28 | — | — | US | disclosed |
| US-20080051451-A1 | Autoimmune conditions and NADPH oxidase defects | BIOVITRUM AB (SE) | 2008-02-28 | — | — | US | disclosed |
| WO-2007104790-A1 | AUTOIMMUNE CONDITIONS AND NADPH OXIDASE DEFECTS | BIOVITRUM AB (PUBL) (SE) | 2007-09-20 | — | — | WO | disclosed |
| WO-2007104790-A1 | AUTOIMMUNE CONDITIONS AND NADPH OXIDASE DEFECTS | BIOVITRUM AB (PUBL) (SE) | 2007-09-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080051451-A1 | Autoimmune conditions and NADPH oxidase defects | CYBB, NOX1, NOX5 | TDP1 1932/4885EGFR 4761/4885LMNA 4180/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.