Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2R | P25116 | 20/20 | 0.67 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.67 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.67 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.67 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.67 |
| ▸ | GPR183 | P32249 | 1/20 | 0.67 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.67 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.67 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14509113 | 0.82 | F2R (0.80) | F2RABCB11ADORA3CHRM1SLC6A2 | |
| SCHEMBL18597708 | 0.81 | F2R (0.79) | F2RABCB11ADORA3CHRM1SLC6A2 | |
| SCHEMBL1106148 | 0.81 | F2R (0.76) | F2RABCB11ADORA3CHRM1SLC6A2 | |
| SCHEMBL1106240 | 0.81 | F2R (0.76) | F2RABCB11ADORA3CHRM1SLC6A2 | |
| SCHEMBL16573430 | 0.81 | F2R (0.70) | F2RABCB11ADORA3CHRM1SLC6A2 | |
| SCHEMBL16901528 | 0.81 | F2R (0.87) | F2RABCB11ADORA3CHRM1SLC6A2 | |
| Vorapaxar SCHEMBL24988797 | 0.80 | F2R (1.00) | F2RABCB11ADORA3CHRM1SLC6A2 | |
| Vorapaxar SCHEMBL14203526 | 0.80 | F2R (1.00) | F2RABCB11ADORA3CHRM1SLC6A2 | |
| Vorapaxar SCHEMBL14203668 | 0.80 | F2R (1.00) | F2RABCB11ADORA3CHRM1SLC6A2 | |
| Vorapaxar SCHEMBL22122697 | 0.80 | F2R (1.00) | F2RABCB11ADORA3CHRM1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2399912-A2 | An exo-selective synthesis of himbacine analogs | Schering Corporation (US) | 2011-12-28 | — | — | EP | disclosed |