Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.36 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.35 |
| ▸ | CDC25B | P30305 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | CPT2 | P23786 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.32 |
| ▸ | KDM4A | O75164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2816326 | 1.00 | BLM (0.50) | BLMLMNAMEN1CYP3A4ALOX15 | |
| SCHEMBL10654543 | 0.87 | BLM (0.39) | BLMFFAR1CPT2TDP1CYP2D6 | |
| SCHEMBL6236490 | 0.85 | CYP2D6 (0.39) | BLMFFAR1CPT2TDP1CYP2D6 | |
| SCHEMBL7710974 | 0.84 | FFAR1 (0.41) | BLMLMNAFFAR1CPT2TDP1 | |
| SCHEMBL9956243 | 0.82 | FFAR1 (0.44) | BLMLMNAFFAR1CPT2TDP1 | |
| SCHEMBL9955921 | 0.82 | FFAR1 (0.44) | BLMLMNAFFAR1CPT2TDP1 | |
| SCHEMBL9955405 | 0.82 | FFAR1 (0.44) | BLMLMNAFFAR1CPT2TDP1 | |
| SCHEMBL9956582 | 0.82 | FFAR1 (0.44) | BLMLMNAFFAR1CPT2TDP1 | |
| SCHEMBL9954618 | 0.82 | FFAR1 (0.44) | BLMLMNAFFAR1CPT2TDP1 | |
| SCHEMBL9956007 | 0.82 | FFAR1 (0.44) | BLMLMNAFFAR1CPT2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2004159-A1 | AUTOIMMUNE CONDITIONS AND NADPH OXIDASE DEFECTS | Biovitrum AB (publ) (SE) | 2008-12-24 | — | — | EP | disclosed |
| WO-2007104790-A1 | AUTOIMMUNE CONDITIONS AND NADPH OXIDASE DEFECTS | BIOVITRUM AB (PUBL) (SE) | 2007-09-20 | — | — | WO | disclosed |