Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2R | P25116 | 19/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13965522 | 0.88 | F2R (0.39) | F2R | |
| SCHEMBL13965525 | 0.88 | F2R (0.39) | F2R | |
| SCHEMBL13965524 | 0.88 | F2R (0.39) | F2R | |
| SCHEMBL13965521 | 0.88 | F2R (0.39) | F2R | |
| SCHEMBL12083875 | 0.86 | F2R (0.43) | F2R | |
| SCHEMBL12083872 | 0.86 | F2R (0.43) | F2R | |
| SCHEMBL12083790 | 0.86 | F2R (0.43) | F2R | |
| SCHEMBL14203714 | 0.86 | F2R (0.43) | F2R | |
| SCHEMBL13337526 | 0.86 | F2R (0.43) | F2R | |
| SCHEMBL12083672 | 0.86 | F2R (0.43) | F2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2399912-B1 | An exo-selective synthesis of himbacine analogs | MERCK SHARP & DOHME (US) | 2015-02-25 | — | — | EP | disclosed |
| EP-2399912-A2 | An exo-selective synthesis of himbacine analogs | Schering Corporation (US) | 2011-12-28 | — | — | EP | disclosed |