Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALCRL | Q16602 | 18/20 | 0.49 |
| ▸ | RAMP1 | O60894 | 3/20 | 0.49 |
| ▸ | CALCA | P06881 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 15/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6221171 | 0.88 | CALCRL (0.61) | CALCRLRAMP1CYP3A4 | |
| SCHEMBL13331684 | 0.85 | CALCRL (0.56) | CALCRLRAMP1CALCACYP3A4 | |
| SCHEMBL13331129 | 0.85 | CALCRL (0.58) | CALCRLRAMP1CYP3A4 | |
| SCHEMBL3315654 | 0.85 | CALCRL (0.57) | CALCRLRAMP1CALCACYP3A4 | |
| SCHEMBL6221778 | 0.84 | CALCRL (0.59) | CALCRLRAMP1CALCACYP3A4 | |
| SCHEMBL13331686 | 0.84 | CALCRL (0.61) | CALCRLRAMP1CYP3A4 | |
| SCHEMBL3315805 | 0.84 | CALCRL (0.61) | CALCRLRAMP1CYP3A4 | |
| SCHEMBL6221733 | 0.84 | CALCRL (0.68) | CALCRLRAMP1CYP3A4 | |
| SCHEMBL3313701 | 0.83 | CALCRL (0.62) | CALCRLRAMP1CYP3A4 | |
| SCHEMBL13331689 | 0.83 | CALCRL (0.62) | CALCRLRAMP1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1558600-B1 | SELECTED CGRP ANTAGONISTS, METHOD FOR PRODUCTION AND USE THEREOF AS MEDICAMENT | BOEHRINGER INGELHEIM PHARMA (DE) | 2008-05-07 | — | — | EP | claimed |