Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALCRL | Q16602 | 19/20 | 0.65 |
| ▸ | RAMP1 | O60894 | 2/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 15/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6222106 | 1.00 | CALCRL (0.65) | CALCRLRAMP1CYP3A4 | |
| SCHEMBL4721384 | 0.96 | CALCRL (0.58) | CALCRLRAMP1CYP3A4 | |
| SCHEMBL4719362 | 0.95 | CALCRL (0.66) | CALCRLRAMP1CYP3A4 | |
| SCHEMBL6261256 | 0.95 | CALCRL (0.66) | CALCRLRAMP1CYP3A4 | |
| SCHEMBL4719838 | 0.94 | CALCRL (0.65) | CALCRLRAMP1CYP3A4 | |
| SCHEMBL4716729 | 0.94 | CALCRL (0.65) | CALCRLRAMP1CYP3A4 | |
| SCHEMBL4716849 | 0.94 | CALCRL (0.74) | CALCRLRAMP1CYP3A4 | |
| SCHEMBL4717049 | 0.93 | CALCRL (0.70) | CALCRLRAMP1CYP3A4 | |
| SCHEMBL3312038 | 0.92 | CALCRL (0.68) | CALCRLRAMP1CYP3A4 | |
| SCHEMBL6222231 | 0.91 | CALCRL (0.62) | CALCRLRAMP1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1558600-B1 | SELECTED CGRP ANTAGONISTS, METHOD FOR PRODUCTION AND USE THEREOF AS MEDICAMENT | BOEHRINGER INGELHEIM PHARMA (DE) | 2008-05-07 | — | — | EP | claimed |
| EP-1558600-B1 | SELECTED CGRP ANTAGONISTS, METHOD FOR PRODUCTION AND USE THEREOF AS MEDICAMENT | BOEHRINGER INGELHEIM PHARMA (DE) | 2008-05-07 | — | — | EP | disclosed |
| EP-1558600-A1 | SELECTED CGRP ANTAGONISTS, METHOD FOR PRODUCTION AND USE THEREOF AS MEDICAMENT | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2005-08-03 | — | — | EP | disclosed |
| WO-2004037810-A1 | SELECTED CGRP ANTAGONISTS, METHOD FOR PRODUCTION AND USE THEREOF AS MEDICAMENT | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2004-05-06 | — | — | WO | disclosed |