Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | GRIA4 | P48058 | 11/20 | 0.40 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.36 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.36 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4714033 | 0.85 | CA1 (0.48) | CA1CA2GRIA4KMT2AHTT | |
| SCHEMBL4022508 | 0.82 | CA1 (0.45) | CA1CA2GRIA4KMT2AHTT | |
| SCHEMBL4022515 | 0.82 | CA1 (0.45) | CA1CA2GRIA4 | |
| SCHEMBL4714206 | 0.81 | CA1 (0.44) | CA1CA2GRIA4KMT2AHTT | |
| SCHEMBL4711948 | 0.74 | CA1 (0.38) | CA1CA2GRIA4 | |
| SCHEMBL4711944 | 0.73 | CA1 (0.37) | CA1CA2GRIA4 | |
| SCHEMBL4712382 | 0.71 | CCR1 (0.41) | KMT2AHTTMEN1 | |
| SCHEMBL10448428 | 0.70 | CA1 (0.61) | CA1CA2GRIA4KMT2AMEN1 | |
| SCHEMBL6990063 | 0.70 | KMT2A (0.43) | CA1CA2KMT2AHTTMEN1 | |
| SCHEMBL5877690 | 0.70 | GRIA4 (0.75) | CA1CA2GRIA4GRIA1GRIA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1986637-A1 | SULFONAMIDE DERIVATIVES FOR THE TREATMENT OF BACTERIAL INFECTIONS | Laboratoires Serono SA (CH) | 2008-11-05 | — | — | EP | claimed |
| WO-2007093557-A1 | SULFONAMIDE DERIVATIVES FOR THE TREATMENT OF BACTERIAL INFECTIONS | LABORATOIRES SERONO S.A. (CH) | 2007-08-23 | — | — | WO | claimed |