Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | F10 | P00742 | 3/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | SYK | P43405 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | CXCR3 | P49682 | 2/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | MYC | P01106 | 2/20 | 0.32 |
| ▸ | WDR5 | P61964 | 2/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4719263 | 1.00 | NOTUM (0.40) | NOTUMMEN1ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL4722851 | 0.94 | F10 (0.33) | NOTUMMEN1KMT2AF10F2 | |
| SCHEMBL4722850 | 0.94 | F10 (0.33) | NOTUMMEN1KMT2AF10F2 | |
| SCHEMBL4720061 | 0.94 | F10 (0.33) | NOTUMMEN1KMT2AF10F2 | |
| SCHEMBL4720066 | 0.94 | F10 (0.33) | NOTUMMEN1KMT2AF10F2 | |
| SCHEMBL4724059 | 0.93 | KMT2A (0.34) | NOTUMMEN1ALDH1A1KMT2AF10 | |
| SCHEMBL4724067 | 0.93 | KMT2A (0.34) | NOTUMMEN1ALDH1A1KMT2AF10 | |
| SCHEMBL4720070 | 0.93 | F10 (0.34) | NOTUMF10F2P2RX7CXCR3 | |
| SCHEMBL4720064 | 0.93 | F10 (0.34) | NOTUMF10F2P2RX7CXCR3 | |
| SCHEMBL4721098 | 0.93 | F10 (0.33) | NOTUMKMT2AF10F2P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1953147-A1 | HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF | Japan Tobacco, Inc. (JP) | 2008-08-06 | — | — | EP | disclosed |