Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 8/20 | 0.36 |
| ▸ | F2 | P00734 | 2/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | CXCR3 | P49682 | 3/20 | 0.33 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4720620 | 1.00 | F10 (0.36) | F10F2P2RX7CXCR3SLC6A9 | |
| SCHEMBL4720716 | 0.94 | F10 (0.36) | F10F2P2RX7CXCR3SLC6A9 | |
| SCHEMBL4720721 | 0.94 | F10 (0.36) | F10F2P2RX7CXCR3SLC6A9 | |
| SCHEMBL4719085 | 0.94 | F10 (0.36) | F10F2P2RX7CXCR3ROCK2 | |
| SCHEMBL4723793 | 0.94 | F10 (0.36) | F10F2P2RX7CXCR3ROCK2 | |
| SCHEMBL4719091 | 0.94 | F10 (0.36) | F10F2P2RX7CXCR3ROCK2 | |
| SCHEMBL4723789 | 0.94 | F10 (0.36) | F10F2P2RX7CXCR3ROCK2 | |
| SCHEMBL4722522 | 0.93 | F10 (0.35) | F10F2P2RX7CXCR3SLC6A9 | |
| SCHEMBL4722526 | 0.93 | F10 (0.35) | F10F2P2RX7CXCR3SLC6A9 | |
| SCHEMBL4719634 | 0.92 | F10 (0.37) | F10F2P2RX7CXCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1953147-A1 | HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF | Japan Tobacco, Inc. (JP) | 2008-08-06 | — | — | EP | disclosed |