Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 6/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 12/20 | 0.63 |
| ▸ | HTR6 | P50406 | 2/20 | 0.63 |
| ▸ | HTT | P42858 | 1/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4720519 | 0.89 | MAPT (0.61) | NPSR1CYP2C9CYP3A4MAPTHTR6 | |
| SCHEMBL4722891 | 0.87 | MAPT (0.69) | NPSR1CYP2C9CYP3A4MAPTHTR6 | |
| SCHEMBL4721334 | 0.87 | MAPT (0.80) | NPSR1CYP2C9CYP3A4MAPTHTR6 | |
| SCHEMBL4719724 | 0.87 | MAPT (0.59) | NPSR1CYP2C9CYP3A4MAPTHTR6 | |
| SCHEMBL4722246 | 0.86 | MAPT (0.62) | NPSR1CYP2C9CYP3A4MAPTHTR6 | |
| SCHEMBL4766617 | 0.86 | MAPT (0.69) | NPSR1CYP2C9CYP3A4MAPTHTR6 | |
| SCHEMBL4721362 | 0.85 | MAPT (0.56) | NPSR1CYP2C9CYP3A4MAPTHTR6 | |
| SCHEMBL4722367 | 0.85 | MAPT (0.59) | NPSR1CYP2C9CYP3A4MAPTHTR6 | |
| SCHEMBL4721669 | 0.85 | MAPT (0.54) | NPSR1CYP2C9CYP3A4MAPTHTR6 | |
| SCHEMBL4719722 | 0.85 | MAPT (0.56) | NPSR1CYP2C9CYP3A4MAPTHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1953147-A1 | HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF | Japan Tobacco, Inc. (JP) | 2008-08-06 | — | — | EP | disclosed |