Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 | Q9H244 | 17/20 | 0.69 |
| ▸ | GBA1 | P04062 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4721127 | 0.93 | P2RY12 (0.69) | P2RY12GBA1MEN1ALDH1A1KMT2A | |
| SCHEMBL4721910 | 0.92 | P2RY12 (0.68) | P2RY12GBA1MEN1ALDH1A1KMT2A | |
| SCHEMBL4721655 | 0.88 | P2RY12 (0.63) | P2RY12MEN1ALDH1A1KMT2A | |
| SCHEMBL5849255 | 0.88 | P2RY12 (0.75) | P2RY12MEN1ALDH1A1KMT2A | |
| SCHEMBL5849367 | 0.87 | P2RY12 (0.74) | P2RY12MEN1ALDH1A1KMT2A | |
| SCHEMBL5265542 | 0.87 | P2RY12 (0.74) | P2RY12MEN1ALDH1A1KMT2A | |
| SCHEMBL5849412 | 0.87 | P2RY12 (0.74) | P2RY12MEN1ALDH1A1KMT2A | |
| SCHEMBL4722371 | 0.86 | P2RY12 (0.72) | P2RY12MEN1ALDH1A1KMT2A | |
| SCHEMBL5849359 | 0.86 | P2RY12 (0.72) | P2RY12MEN1ALDH1A1KMT2A | |
| SCHEMBL5849493 | 0.85 | P2RY12 (0.71) | P2RY12MEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1896483-A2 | 4-PIPERAZINYLTHIENO [2, 3-D] PYRIMIDINE COMPOUNDS AS PLATELET AGGREGATION INHIBITORS | Pharmacia & Upjohn Company LLC (US) | 2008-03-12 | — | — | EP | disclosed |
| WO-2006103544-A2 | 4-PIPERAZINYLTHIENO [2, 3-D] PYRIMIDINE COMPOUNDS AS PLATELET AGGREGATION INHIBITORS | PHARMACIA & UPJOHN COMPANY LLC (US) | 2006-10-05 | — | — | WO | disclosed |