Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | HTR6 | P50406 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.43 |
| ▸ | FBP1 | P09467 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4721484 | 0.93 | MAPT (0.67) | MAPTNPSR1LMNAGAAHTT | |
| SCHEMBL4722394 | 0.87 | MAPT (0.55) | MAPTNPSR1LMNAGAAHTT | |
| SCHEMBL4720311 | 0.82 | MAPT (0.63) | MAPTNPSR1LMNAGAAHTT | |
| SCHEMBL4724747 | 0.81 | NPSR1 (0.74) | MAPTNPSR1LMNAGAAHTT | |
| SCHEMBL4723874 | 0.81 | MAPT (0.59) | MAPTNPSR1LMNAGAAHTT | |
| SCHEMBL4722447 | 0.81 | MAPT (0.61) | MAPTNPSR1LMNAGAAHTT | |
| SCHEMBL4724164 | 0.80 | NPSR1 (0.83) | MAPTNPSR1LMNAGAAHTT | |
| SCHEMBL4724101 | 0.80 | MAPT (0.65) | MAPTNPSR1LMNAGAAHTT | |
| SCHEMBL14102059 | 0.80 | NPSR1 (0.45) | MAPTNPSR1LMNAGAAHTT | |
| SCHEMBL4721037 | 0.78 | NPSR1 (0.72) | MAPTNPSR1LMNAGAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1953147-A1 | HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF | Japan Tobacco, Inc. (JP) | 2008-08-06 | — | — | EP | disclosed |
| EP-1953147-A1 | HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF | Japan Tobacco, Inc. (JP) | 2008-08-06 | — | — | EP | disclosed |