Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.51 |
| ▸ | PKM | P14618 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.45 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.45 |
| ▸ | GAK | O14976 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4724283 | 0.89 | MAPT (0.50) | MAPTPKMLMNATDP1MAPK1 | |
| SCHEMBL4721108 | 0.88 | MAPT (0.48) | MAPTPKMLMNATDP1MAPK1 | |
| SCHEMBL4722671 | 0.88 | MAPT (0.50) | MAPTPKMLMNATDP1MAPK1 | |
| SCHEMBL4720172 | 0.88 | MAPT (0.54) | MAPTPKMLMNATDP1MAPK1 | |
| SCHEMBL4722824 | 0.88 | MAPT (0.47) | MAPTPKMLMNATDP1MAPK1 | |
| SCHEMBL4721264 | 0.88 | MAPT (0.56) | MAPTPKMLMNATDP1MAPK1 | |
| SCHEMBL4721593 | 0.88 | MAPT (0.56) | MAPTPKMLMNATDP1MAPK1 | |
| SCHEMBL4719536 | 0.88 | MAPT (0.51) | MAPTPKMLMNATDP1MAPK1 | |
| SCHEMBL4723306 | 0.88 | NPSR1 (0.48) | MAPTPKMLMNATDP1MAPK1 | |
| SCHEMBL4720627 | 0.87 | MAPT (0.49) | MAPTPKMLMNATDP1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1953147-A1 | HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF | Japan Tobacco, Inc. (JP) | 2008-08-06 | — | — | EP | disclosed |