Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR8 | P51685 | 14/20 | 0.72 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.52 |
| ▸ | DRD2 | P14416 | 2/20 | 0.40 |
| ▸ | DRD3 | P35462 | 2/20 | 0.40 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4722649 | 1.00 | CCR8 (0.72) | CCR8KCNH2DRD2DRD3SLC2A1 | |
| SCHEMBL3930467 | 0.84 | CCR8 (1.00) | CCR8KCNH2 | |
| SCHEMBL3930474 | 0.84 | CCR8 (1.00) | CCR8KCNH2 | |
| SCHEMBL3919790 | 0.71 | CCR8 (1.00) | CCR8KCNH2 | |
| SCHEMBL3919797 | 0.71 | CCR8 (1.00) | CCR8KCNH2 | |
| SCHEMBL4721447 | 0.69 | CCR8 (0.74) | CCR8KCNH2DRD2DRD3 | |
| SCHEMBL3177394 | 0.68 | CCR8 (1.00) | CCR8KCNH2 | |
| SCHEMBL29422855 | 0.68 | CCR8 (1.00) | CCR8KCNH2 | |
| SCHEMBL3930454 | 0.68 | CCR8 (0.72) | CCR8KCNH2 | |
| SCHEMBL3930460 | 0.68 | CCR8 (0.72) | CCR8KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1567520-B1 | QUINOLINES AND NITROGENATED DERIVATIVES THEREOF AND THEIR USE AS ANTIBACTERIAL AGENTS | GLAXO GROUP LTD (GB) | 2008-10-15 | — | — | EP | claimed |