Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.50 |
| ▸ | NFE2L2 | Q16236 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CMA1 | P23946 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL144447 | 0.76 | MAOB (0.59) | MAOBMAPK1ALDH1A1LMNATRPA1 | |
| SCHEMBL28582529 | 0.76 | MAOB (0.59) | MAOBMAPK1ALDH1A1LMNATRPA1 | |
| SCHEMBL9427090 | 0.76 | MAOB (0.59) | MAOBMAPK1ALDH1A1LMNATRPA1 | |
| SCHEMBL2563361 | 0.76 | MAOB (0.59) | MAOBMAPK1ALDH1A1LMNATRPA1 | |
| SCHEMBL9790648 | 0.76 | MAOB (0.59) | MAOBMAPK1ALDH1A1LMNATRPA1 | |
| SCHEMBL9427086 | 0.76 | MAOB (0.59) | MAOBMAPK1ALDH1A1LMNATRPA1 | |
| SCHEMBL23458007 | 0.76 | MAOB (1.00) | MAOBMAPK1ALDH1A1LMNATRPA1 | |
| Benzene SCHEMBL9803304 | 0.76 | MAOB (1.00) | MAOBMAPK1ALDH1A1LMNATRPA1 | |
| SCHEMBL6853572 | 0.76 | MAOB (1.00) | MAOBMAPK1ALDH1A1LMNATRPA1 | |
| SCHEMBL5875512 | 0.76 | MAOB (1.00) | MAOBMAPK1ALDH1A1LMNATRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1755396-B1 | PIPERAZIN DERIVATIVES AND THEIR USE IN CONTROLLING PESTS | SYNGENTA PARTICIPATIONS AG (CH) | 2014-06-18 | — | — | EP | disclosed |
| EP-1880996-A1 | Spiroindolinepiperidine derivatives | Syngenta Limited (GB) | 2008-01-23 | — | — | EP | disclosed |