Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR9 | P51686 | 2/20 | 0.33 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.33 |
| ▸ | PFKFB4 | Q16877 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.32 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.32 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.32 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.32 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.32 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.32 |
| ▸ | MET | P08581 | 1/20 | 0.32 |
| ▸ | GLO1 | Q04760 | 2/20 | 0.32 |
| ▸ | CKS1B | P61024 | 1/20 | 0.32 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | BRD4 | O60885 | 2/20 | 0.31 |
| ▸ | WDR5 | P61964 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4720610 | 0.91 | MEN1 (0.33) | CCR9MEN1KMT2AHPGDSMN1; SMN2 | |
| SCHEMBL4723380 | 0.88 | BRAF (0.34) | CCR9CKS1BSKP2MEN1KMT2A | |
| SCHEMBL4723485 | 0.87 | MEN1 (0.39) | CYP2D6MEN1KMT2AHPGDSMN1; SMN2 | |
| SCHEMBL4722898 | 0.86 | MEN1 (0.35) | MEN1KMT2AHPGDSMN1; SMN2NPSR1 | |
| SCHEMBL4723628 | 0.86 | MEN1 (0.36) | CCR9MEN1KMT2AHPGDSMN1; SMN2 | |
| SCHEMBL4722814 | 0.84 | MEN1 (0.36) | CCR9CYP2D6MEN1KMT2AJAK2 | |
| SCHEMBL4719533 | 0.83 | PDE4A (0.38) | MEN1KMT2AHPGDSMN1; SMN2NPSR1 | |
| SCHEMBL4721827 | 0.80 | PDE4A (0.35) | CCR9PFKFB3PFKFB4MEN1KMT2A | |
| SCHEMBL4723938 | 0.80 | MEN1 (0.34) | CCR9MEN1KMT2AHPGDSMN1; SMN2 | |
| SCHEMBL4720482 | 0.80 | MEN1 (0.34) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1953147-A1 | HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF | Japan Tobacco, Inc. (JP) | 2008-08-06 | — | — | EP | disclosed |