Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 13/20 | 0.39 |
| ▸ | NPY1R | P25929 | 1/20 | 0.36 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.36 |
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL472338 | 1.00 | PTGIR (0.39) | PTGIRNPY1RNPY5RSLC18A3CHRM2 | |
| SCHEMBL472494 | 0.78 | CA1 (0.43) | PTGIRPPARG | |
| SCHEMBL472492 | 0.78 | CA1 (0.43) | PTGIRPPARG | |
| SCHEMBL19183218 | 0.76 | SLC1A3 (0.45) | PTGIR | |
| SCHEMBL23059594 | 0.72 | CHRM2 (0.39) | CHRM2CHRM1CHRM3 | |
| SCHEMBL24191927 | 0.72 | CHRM2 (0.39) | CHRM2CHRM1CHRM3 | |
| SCHEMBL5129065 | 0.72 | TRPV1 (0.41) | NPY1RNPY5RSLC18A3CHRM2CHRM1 | |
| SCHEMBL205316 | 0.67 | SLC18A3 (0.44) | SLC18A3CHRM2CHRM1CHRM3 | |
| SCHEMBL287422 | 0.67 | SLC18A3 (0.44) | SLC18A3CHRM2CHRM1CHRM3 | |
| SCHEMBL299965 | 0.67 | SLC18A3 (0.44) | SLC18A3CHRM2CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2412372-A1 | 2-Aminooxazole derivatives for use as TRPV1 antagonists for treating i.a. pain, inflammation, neurodegenerative diseases or gastrointestinal diseases | Abbott Laboratories (US) | 2012-02-01 | — | — | EP | disclosed |
| US-7998993-B2 | TRPV1 antagonists | ABBOTT LABORATORIES (US) | 2011-08-16 | — | — | US | disclosed |