Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 6/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | FSHR | P23945 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CXCR3 | P49682 | 3/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4724071 | 1.00 | F10 (0.33) | F10F2FSHRKMT2ANOTUM | |
| SCHEMBL4724059 | 0.97 | KMT2A (0.34) | F10F2KMT2ANOTUMMAPT | |
| SCHEMBL4724067 | 0.97 | KMT2A (0.34) | F10F2KMT2ANOTUMMAPT | |
| SCHEMBL4720367 | 0.95 | F10 (0.33) | F10F2KMT2ANOTUMGAA | |
| SCHEMBL4721094 | 0.94 | F10 (0.33) | F10F2KMT2ANOTUMGAA | |
| SCHEMBL4720070 | 0.93 | F10 (0.34) | F10F2NOTUMP2RX7CXCR3 | |
| SCHEMBL4720064 | 0.93 | F10 (0.34) | F10F2NOTUMP2RX7CXCR3 | |
| SCHEMBL4719263 | 0.92 | NOTUM (0.40) | F10F2KMT2ANOTUMMAPT | |
| SCHEMBL4722850 | 0.92 | F10 (0.33) | F10F2KMT2ANOTUMP2RX7 | |
| SCHEMBL4720061 | 0.92 | F10 (0.33) | F10F2KMT2ANOTUMP2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1953147-A1 | HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF | Japan Tobacco, Inc. (JP) | 2008-08-06 | — | — | EP | disclosed |