SCHEMBL4724129

SCHEMBL4724129

NC(C(=O)O)C(=O)c1ncc2cc(Oc3ccccc3)ccc2c1O

nearest known ligand 0.69

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
EGLN2 Q96KS0 19/20 0.69
EGLN1 Q9GZT9 15/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL966034 0.91 EGLN2 (0.58) EGLN2EGLN1
SCHEMBL1527778 0.88 EGLN2 (0.55) EGLN2EGLN1
SCHEMBL6908613 0.87 EGLN2 (0.54) EGLN2EGLN1
SCHEMBL1527732 0.86 EGLN2 (0.56) EGLN2EGLN1
SCHEMBL5140999 0.85 EGLN2 (0.57) EGLN2EGLN1
SCHEMBL30394217 0.85 EGLN1 (0.67) EGLN2EGLN1
SCHEMBL29726498 0.85 EGLN1 (0.70) EGLN2EGLN1
SCHEMBL21361727 0.85 EGLN1 (0.70) EGLN2EGLN1
Acetic Acid SCHEMBL28993792 0.82 EGLN1 (0.64) EGLN2EGLN1
SCHEMBL15268520 0.82 EGLN2 (1.00) EGLN2EGLN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1578431-A4 FAT REGULATION FIBROGEN INC (US) 2008-04-23 EP disclosed
EP-1578431-A2 FAT REGULATION FIBROGEN, INC. (US) 2005-09-28 EP disclosed
WO-2004052285-A2 FAT REGULATION FIBROGEN, INC. (US) 2004-06-24 WO disclosed