Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | MMP9 | P14780 | 2/20 | 0.47 |
| ▸ | MMP1 | P03956 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.47 |
| ▸ | ABL1 | P00519 | 1/20 | 0.46 |
| ▸ | CSF1R | P07333 | 1/20 | 0.46 |
| ▸ | IGF1R | P08069 | 1/20 | 0.46 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.46 |
| ▸ | KIT | P10721 | 1/20 | 0.46 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.46 |
| ▸ | FLT1 | P17948 | 1/20 | 0.46 |
| ▸ | FLT4 | P35916 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | TEK | Q02763 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4727611 | 0.92 | ABL1 (0.51) | MMP9MMP1CYP3A4ABL1CSF1R | |
| SCHEMBL4777946 | 0.91 | DEGS1 (0.47) | KMT2ANPC1RAB9AMMP9MMP1 | |
| Hydrochloric Acid SCHEMBL4725333 | 0.91 | ABL1 (0.50) | NPC1RAB9AMMP9MMP1CYP3A4 | |
| SCHEMBL4730317 | 0.90 | KDR (0.51) | KMT2ANPC1RAB9AMMP9MMP1 | |
| SCHEMBL4726122 | 0.90 | KDR (0.46) | KMT2AMMP9MMP1ABL1CSF1R | |
| SCHEMBL4779689 | 0.90 | SERPINE1 (0.49) | KMT2AMMP9MMP1ABL1CSF1R | |
| SCHEMBL4727987 | 0.89 | CFTR (0.53) | MMP9MMP1ABL1CSF1RIGF1R | |
| SCHEMBL4726501 | 0.89 | CYP3A4 (0.49) | KMT2ANPC1RAB9ACYP3A4MEN1 | |
| SCHEMBL4725931 | 0.89 | CYP3A4 (0.49) | KMT2ANPC1RAB9AMMP9MMP1 | |
| Hydrochloric Acid SCHEMBL4725088 | 0.88 | CYP3A4 (0.48) | KMT2ANPC1RAB9ACYP3A4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008021725-A2 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2008-02-21 | — | — | WO | claimed |
| WO-2008021725-A2 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2008-02-21 | — | — | WO | disclosed |