Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3A | P49840 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15570455 | 0.65 | GSK3A (0.42) | GSK3AGSK3BCRBN | |
| SCHEMBL277815 | 0.63 | — | — | |
| SCHEMBL1126452 | 0.63 | GSK3A (0.39) | GSK3AGSK3B | |
| SCHEMBL13587063 | 0.62 | — | — | |
| SCHEMBL5468608 | 0.60 | GSK3A (0.40) | GSK3AGSK3B | |
| SCHEMBL9527717 | 0.59 | GSK3A (0.46) | GSK3AGSK3B | |
| SCHEMBL10381529 | 0.59 | GSK3A (0.46) | GSK3AGSK3B | |
| SCHEMBL943110 | 0.59 | GSK3A (0.46) | GSK3AGSK3B | |
| SCHEMBL366153 | 0.58 | GSK3A (0.71) | GSK3AGSK3B | |
| SCHEMBL30766303 | 0.58 | GSK3A (0.43) | GSK3AGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008020180-A2 | METHODS OF INCREASING THE SENSITIVITY OF CANCER CELLS TO DNA DAMAGE | KUDOS PHARMACEUTICALS LIMITED (GB) | 2008-02-21 | — | — | WO | disclosed |
| EP-1684736-A1 | DNA DAMAGE REPAIR INHIBITORS FOR TREATMENT OF CANCER | Kudos Pharmaceuticals Limited (GB) | 2006-08-02 | — | — | EP | disclosed |
| WO-2005053662-A1 | DNA DAMAGE REPAIR INHIBITORS FOR TREATMENT OF CANCER | KUDOS PHARMACEUTICALS LIMITED (GB) | 2005-06-16 | — | — | WO | disclosed |