Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 20/20 | 0.70 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.70 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2686453 | 1.00 | HDAC1 (0.70) | HDAC1HDAC2HDAC3 | |
| SCHEMBL2693173 | 0.93 | HDAC1 (0.69) | HDAC1HDAC2HDAC3 | |
| SCHEMBL2692243 | 0.91 | HDAC1 (0.70) | HDAC1HDAC2HDAC3 | |
| SCHEMBL5547900 | 0.90 | HDAC1 (0.65) | HDAC1HDAC2HDAC3 | |
| SCHEMBL2687151 | 0.88 | HDAC1 (0.67) | HDAC1HDAC2HDAC3 | |
| SCHEMBL2686110 | 0.85 | HDAC1 (0.66) | HDAC1HDAC2HDAC3 | |
| SCHEMBL4451154 | 0.85 | HDAC1 (0.70) | HDAC1HDAC2HDAC3 | |
| SCHEMBL14775884 | 0.84 | HDAC1 (0.65) | HDAC1HDAC2HDAC3 | |
| SCHEMBL2684783 | 0.83 | HDAC1 (0.65) | HDAC1HDAC2HDAC3 | |
| SCHEMBL14775832 | 0.83 | HDAC1 (0.65) | HDAC1HDAC2HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1991226-A2 | INHIBITORS OF HISTONE DEACETYLASE | Merck & Co., Inc. (US) | 2008-11-19 | — | — | EP | disclosed |
| WO-2007100657-A2 | INHIBITORS OF HISTONE DEACETYLASE | MERCK & CO., INC. (US) | 2007-09-07 | — | — | WO | disclosed |