Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 3/20 | 0.72 |
| ▸ | MAPT | P10636 | 14/20 | 0.69 |
| ▸ | MEN1 | O00255 | 11/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 11/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.69 |
| ▸ | LMNA | P02545 | 7/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.69 |
| ▸ | HPGD | P15428 | 3/20 | 0.69 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.69 |
| ▸ | RAB9A | P51151 | 2/20 | 0.69 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.69 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.67 |
| ▸ | POLB | P06746 | 4/20 | 0.66 |
| ▸ | RECQL | P46063 | 1/20 | 0.66 |
| ▸ | NPC1 | O15118 | 1/20 | 0.66 |
| ▸ | HTT | P42858 | 1/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.64 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.63 |
| ▸ | USP2 | O75604 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7722872 | 0.90 | MAPT (0.75) | NPY5RMAPTMEN1KMT2AKDM4E | |
| SCHEMBL4729795 | 0.87 | MAPT (0.66) | NPY5RMAPTMEN1KMT2AKDM4E | |
| SCHEMBL4726728 | 0.87 | NPY5R (0.58) | NPY5RMAPTMEN1KMT2AKDM4E | |
| SCHEMBL6226561 | 0.87 | MAPT (0.74) | NPY5RMAPTMEN1KMT2AKDM4E | |
| SCHEMBL4726912 | 0.86 | NPY5R (0.66) | NPY5RMAPTMEN1KMT2AKDM4E | |
| SCHEMBL4725807 | 0.86 | MAPT (0.72) | NPY5RMAPTMEN1KMT2AKDM4E | |
| SCHEMBL4728014 | 0.86 | MAPT (0.72) | NPY5RMAPTMEN1KMT2AKDM4E | |
| SCHEMBL14082583 | 0.85 | MAPT (0.63) | NPY5RMAPTMEN1KMT2AKDM4E | |
| SCHEMBL14252937 | 0.84 | MAPT (0.64) | MAPTMEN1KMT2AKDM4ELMNA | |
| SCHEMBL4728662 | 0.84 | MAPT (0.70) | NPY5RMAPTMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008021745-A2 | HEPATITIS C VIRUS ENTRY INHIBITORS | ITHERX PHARMACEUTICALS, INC. (US) | 2008-02-21 | — | — | WO | disclosed |
| US-6399631-B1 | 3-AMIDO OR 3-SULFONAMIDO; EATING DISORDERS IN HUMANS, DOGS AND CATS | PFIZER INC. | 2002-06-04 | — | — | US | disclosed |